Periarticular Injection After Total Knee Arthroplasty Using Liposomal Bupivacaine vs a Modified Ranawat Suspension: A Prospective, Randomized Study

Collis, Philip; Hunter, Allison M.; Vaughn, Michael D; Carreon, Leah Y.; Huang, Jiapeng; Malkani, Arthur L.

doi:10.1016/j.arth.2015.09.025

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Cited by 69 publications

(57 citation statements)

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“…[ [24][25][26][27][28][29][30]. The use of LB in the spine has not been investigated near the extent as it has been in TKA and the results from these studies have yet to yield a definitive conclusion.…”

Section: Resultsmentioning

confidence: 99%

The Efficacy of Liposomal Bupivacaine in Lumbar Spine Surgery

Gannon¹

2018

SCTI

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Section: Resultsmentioning

confidence: 99%

The Efficacy of Liposomal Bupivacaine in Lumbar Spine Surgery

Gannon¹

2018

SCTI

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“…In another RCT from Bramlett et al [22] In a recent RCT, Collis et al [23] compared liposomal bupivacaine injection with a mixture of ropivacaine, epinephrine, ketorolac and clonidine. Collis et al…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Efficacy of Liposomal Bupivacaine Infiltrated into the Posterior Capsule for Postoperative Analgesia after Total Knee Arthroplasty—A Randomized Double Blind Clinical Trial

Garg¹,

Gupta²,

Kang³

et al. 2017

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Achieving adequate control of postsurgical pain remains a challenge in patients undergoing Total Knee Arthroplasty (TKA). The objective of this study was to assess if liposomal bupivacaine injected into the posterior capsule, in combination with a femoral nerve block and multimodal pain control regimen, would result in better pain control. The two groups were similar with regards to demographics and method of intraoperative anesthesia. Infiltration into the posterior capsule with liposomal bupivacaine had significantly lower resting pain scores compared to the saline group. Patients in the liposomal bupivacaine group also used slightly less breakthrough narcotic (5.75 to 4.31 mg of morphine equivalence). We recommend the use of infiltration of liposomal bupivacaine into the posterior capsule as an adjunct in multimodal analgesia in TKA patients to reduce pain and resultant narcotic use.

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“…More recently, prospective studies were performed and compared the PAI with standard bupivacaine to the extended-release liposomal bupivacaine. Once again, in this randomized trial, the liposomal bupivacaine did not demonstrate superiority in terms of pain management, but it slighlty improved walking distances after TKA [6]. The additional cost of liposomal bupivacaine was not justified [15].…”

mentioning

confidence: 93%