Pericardial Disease: Diagnosis and Management

Khandaker, Masud H.; Espinosa, Raúl E.; Nishimura, Rick A.; Sinak, Lawrence J.; Hayes, Sharonne N.; Melduni, Rowlens M.; Oh, Jae K.

doi:10.4065/mcp.2010.0046

Cited by 293 publications

(230 citation statements)

References 105 publications

Supporting

Mentioning

206

Contrasting

Unclassified

Order By: Relevance

“…Approximately 1 of every 4 patients with acute pericarditis has at least 1 episode of relapse. [1][2][3][4] Many of these patients are adequately treated medically for their initial relapse and often are never symptomatic again. However, a subset of patients experience chronic relapsing pericarditis, and although the disease is not life-threatening, it can have a substantial effect on quality of life.…”

mentioning

confidence: 99%

Pericardiectomy vs Medical Management in Patients With Relapsing Pericarditis

Khandaker

Schaff

Greason

et al. 2012

Mayo Clinic Proceedings

Self Cite

View full text Add to dashboard Cite

Objective: To determine whether surgical pericardiectomy is a safe and effective alternative to medical management for chronic relapsing pericarditis. Patients and Methods: Retrospective review of 184 patients presenting to the Mayo Clinic in Rochester, Minnesota, from January 1, 1994, through December 31, 2005, with persistent relapsing pericarditis identified 58 patients who had a pericardiectomy after failed medical management and 126 patients who continued with medical treatment only. The primary outcome variables were in-hospital postoperative mortality or major morbidity, all-cause death, time to relapse, and medication use. Results: Mean Ϯ SD follow-up was 5.5Ϯ3.5 years in the surgical group and 5.4Ϯ4.4 years in the medical treatment group. At baseline, patients in the surgical group had higher mean relapses (6.9 vs 5.5; Pϭ.01), were more likely to be taking colchicine ( than the medical treatment group. Perioperative mortality (0%) and major morbidity (3%; nϭ2) were minimal. Kaplan-Meier analysis revealed no differences in all-cause death at follow-up (Pϭ.26); however, the surgical group had a markedly decreased relapse rate compared with the medical treatment group (Pϭ.009). Medication use was notably reduced after pericardiectomy. Conclusion: In patients with chronic relapsing pericarditis in whom medical management has failed, surgical pericardiectomy is a safe and effective method of relieving symptoms.

show abstract

mentioning

confidence: 99%

Pericardiectomy vs Medical Management in Patients With Relapsing Pericarditis

Khandaker

Schaff

Greason

et al. 2012

Mayo Clinic Proceedings

Self Cite

View full text Add to dashboard Cite

show abstract

“…• Disfunción de cadena respiratoria (complejo III) [46] • Baja producción de ATP [46], [47] • Inactivación apoptosis por señalización mitocondrial [48] • Alteración membrana y ADN mitocondrial [49] • Inmunomoduladores e inmunosupresores [50] • Inhibidores de la enzima de conversión de la angiotensina, Bloqueo del receptor de la angiotensina [51] • Diuréticos [51] • Asistencia ventricular [51] • Terapia antiviral (En investigación) [51] Pericarditis Inflamación del pericardio Causa: [52] • Virus, bacterias…”

Section: • Cardiomiopatia Dilatadaunclassified

Rol de la función mitocondrial en el corazón y sus implicaciones en disfunciones cardíacas

Cañas-Arboleda

Franco‐Sierra

2017

ing. cienc.

View full text Add to dashboard Cite

Rol de la función mitocondrial en el corazón y sus implicaciones en disfunciones cardíacas Resumen En este artículo de revisión, examinamos el papel de la mitocondria en el buen funcionamiento del corazón, y en la generación de diversas afecciones cardíacas, las cuales están caracterizadas por una baja producción de energía por parte de las mitocondrias y, por ende, hay un aumento en la pérdida de cardiomiocitos que conlleva al mal funcionamiento del corazón. Se ha determinado, que ciertas disfunciones mitocondriales asociadas a trastornos cardíacos se relacionan con alteraciones del sistema de fosforilación oxidativa, así como, con la disminución de ciertos componentes estructurales como la cardiolipina y la formación de supercomplejos. Se estima que cerca del 2.3 % de la población colombiana puede presentar una prevalencia a la falla cardíaca. La presente revisión tiene como objetivo dar a conocer los avances investigativos relacionados con enfermedades cardíacas ocasionadas por disfunción mitocondrial, así como, la identificación de diferentes investigaciones dirigidas en la creación de alternativas de tratamiento para dichas patologías, todo esto con el fin de contribuir Universidad EAFIT 233|

show abstract

“…1 Dyspnea and congestive symptoms are common nonspecific presenting symptoms that require further evaluation for clinching the diagnosis. Conventional CT scanners are used to evaluate circum ferential pericardial thickness and are considered supe rior to TTE for surgical planning.…”

Section: Introductionmentioning

confidence: 99%

Modification in Surgical Plan following Intraoperative Detection of Co-existent Right Atrial Thrombus by Transesophageal Echocardiography in Chronic Constrictive Pericarditis

Mahajan¹,

Ganesan²

2017

Journal of Perioperative Echocardiography

View full text Add to dashboard Cite

Introduction Chronic constrictive pericarditis (CCP) is common in developing countries, tuberculosis being the most common cause. Dyspnea and congestive symptoms are the most common nonspecific presenting symptoms that require further evaluation for clinching the diagnosis. Coexistent right atrial (RA) thrombus and CCP are rare occurrences. Preoperative detection of RA thrombus is very important to avoid the risk of pulmonary thromboembolism during pericardiectomy or cannulation for establishing cardiopulmonary bypass (CPB). Perioperative echocardiography may play a crucial role in this setting. We report a case of CCP in which preoperative transesophageal echocardiography (TEE) detected RA thrombus that led to change in surgical plan and provided continuous monitoring during surgery. Case Report A 14-year-old male presented with a history of abdominal distension and pedal edema for 5 months. Physical examination revealed raised jugular venous pulse with normal heart sounds and no murmurs. Transthoracic echocardiography (TTE) revealed constrictive physiology and thickened pericardium. After induction of anesthesia, TEE revealed an irregular hyperechoic mass (50 × 36 × 30 mm) in the RA free wall that was not detected on preoperative TTE and computerized tomography (CT). Thickened pericardium all around mandated limited pericardiectomy under TEE guidance to allow bicaval cannulation for establishing CPB. This was followed by surgical removal of the thrombus and remaining pericardiectomy using CPB. His postoperative period was uneventful and the patient was discharged home on postoperative day 7. Conclusion The TEE may be instrumental in diagnosis of coexistent RA thrombus in the case of CCP resulting in major change in surgical plan and providing perioperative monitoring to avert significant morbidity and mortality. How to cite this article Ganesan R, Kumar B, Munirathinam GK, Bhat I, Mahajan S. Modification in Surgical Plan following Intraoperative Detection of Co-existent Right Atrial Thrombus by Transesophageal Echocardiography in Chronic Constrictive Pericarditis. J Perioper Echocardiogr 2017;5(1):34-37.

show abstract

Pericardial Disease: Diagnosis and Management

Cited by 293 publications

References 105 publications

Pericardiectomy vs Medical Management in Patients With Relapsing Pericarditis

Pericardiectomy vs Medical Management in Patients With Relapsing Pericarditis

Rol de la función mitocondrial en el corazón y sus implicaciones en disfunciones cardíacas

Modification in Surgical Plan following Intraoperative Detection of Co-existent Right Atrial Thrombus by Transesophageal Echocardiography in Chronic Constrictive Pericarditis

Contact Info

Product

Resources

About