Pericardial involvement in a common B‐cell acute lymphoblastic leukemia patient

Abstract

A 66-year-old male with 6 months history of acute lymphoblastic leukemia (ALL) present to the outpatient for the follow up. The peripheral blood and bone marrow (Figure 1A) smear show no abnormal cell. But the pericardial fluid was found by the ultrasound by routine examination, pericardiocentesis was performed and a large number of lymphocytic leukemia like blast was found in the pericardial effusion (Figure 1B). Furthermore, these abnormal B cells (85.2%) were confirmed by the flow cytometry, with the phenotype of CD19 + , CD10 ++ , CD38 + , κ À , λ À , and sIgM À . Thus, a diagnosis of pericardial involvement by the relapsed ALL was established. (A) (B)F I G U R E 1 The smear of the bone marrow aspirate and pericardial fluid of a pericardial involvement in a common B-cell ALL patient. Bone marrow aspirate smear (A) and abundant lymphoblastic leukemia cells in the pericardial fluid (B) in this common B-cell ALL patient. (Â1000, Wright-Giemsa staining)Jing He, Yushan Zhang, and Zhenni Wang contribute equally to this work.

Concurrent Pleural and Pericardial Involvement in a Patient With De Novo Pure Erythroid Leukemia

“…Pleural fluid occurrence is more frequent in T-lymphoblastic leukemia/lymphoma, followed by AML. He, et al [8] reported a male patient diagnosed as having B-cell acute lymphoblastic leukemia, in whom pericardial effusion was incidentally discovered during follow-up.…”

“…He, et al . [ 8 ] reported a male patient diagnosed as having B-cell acute lymphoblastic leukemia, in whom pericardial effusion was incidentally discovered during follow-up.…”