2017
DOI: 10.5935/abc.20170155
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Pericardial Parietal Mesothelial Cells: Source of the Angiotensin-Converting-Enzyme of the Bovine Pericardial Fluid

Abstract: BackgroundAngiotensin II (Ang II), the primary effector hormone of the renin-angiotensin system (RAS), acts systemically or locally, being produced by the action of angiotensin-converting-enzyme (ACE) on angiotensin I. Although several tissue RASs, such as cardiac RAS, have been described, little is known about the presence of an RAS in the pericardial fluid and its possible sources. Locally produced Ang II has paracrine and autocrine effects, inducing left ventricular hypertrophy, fibrosis, heart failure and … Show more

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“…However, we observed no pleural effusions in those individuals. Future research is required to explain the clinical effects of angiogenesis and an increased activity of the angiotensin converting enzyme receptor in pericardial mesothelial cells related to SARS-CoV-2 infection [39,40].…”
Section: Covid-19 and Pericarditismentioning
confidence: 99%
“…However, we observed no pleural effusions in those individuals. Future research is required to explain the clinical effects of angiogenesis and an increased activity of the angiotensin converting enzyme receptor in pericardial mesothelial cells related to SARS-CoV-2 infection [39,40].…”
Section: Covid-19 and Pericarditismentioning
confidence: 99%