Periductal stromal tumor of the breast in a young lady: A case report

Abstract

We present the case of a 30‐year‐old lady who underwent a core needle biopsy for a BIRADS 4 lesion of her left breast and was diagnosed as having a cellular fibroadenoma. The final diagnosis after excision returned to be a periductal stromal tumor (PST). An extremely rare entity, the PST is actually classified as a subtype of phyllodes tumor, with specific criteria that are only found upon histological examination of the specimen. Care should be taken when considering the diagnosis of fibroadenoma based only on clinical, radiological, and biopsy findings. Any nonclassical, clinical, or radiological findings should prompt a wide excision. Prognosis is generally good when clear margins are obtained and in the absence of malignant heterologous elements.

Imaging Features of Breast Periductal Stromal Tumor: A Case Report

“…According to the largest case serial report of PDST by Burga et al (6), PDST is more commonly seen in perimenopausal and postmenopausal women (6); however, a single case of PDST in a 14-year-old girl has also been reported (8). The reported mass size was diversified between 0.2 and 20 cm (1-6, 14-16).…”

“…Breast periductal stromal tumor (PDST) is a rare condition and accounts for less than 1% of all breast malignancies. As far as we know, only sporadic cases were reported (1)(2)(3)(4)(5)(6)(7)(8)(9). As a biphasic tumor, PDST shows both benign ductal epithelium and non-phyllodes sarcomatous stroma.…”