Perihepatic Lymph Nodes as a Marker of Antiviral Response in Patients with Chronic Hepatitis C Infection

Abstract

Total perihepatic lymph node volume changes according to the antiviral response and leads to progressive normalization of the perihepatic lymph node volume in sustained virologic responders. A decrease in the perihepatic lymph node volume is associated with an improvement in liver histology.

Clinical significance of ultrasonographic imaging of the common hepatic arterial lymph node (No. 8 LN) in chronic liver diseases

“…no. 8 ln has previously been observed in 77-91% of cHc patients (3)(4)(5)(6)(7)(8)(9)(10)(11)(12) and 96% of cHB patients (14). in our study, the no.…”

“…regarding lymph node size, there have been many reports of the relationship between chronic liver diseases and lymph nodes investigated by ultrasonography (8)(9)(10)(11)(12). However, none of the studies used the ln index (major x minor axis of the lymph node) for the side index lymph nodes, established the aST, aspartate aminotransferase; alT, alanine aminotransferase; ALB, albumin; ALP, alkaline phosphatase; γ-GTP,γ-glutamyltranspeptidase; cHe, cholinesterase; PlT, platelets.…”

“…The detection of intra-abdominal lymph nodes by ultrasonography is useful for the detection of lymph node metastasis from malignant tumors and the enlargement of lymph nodes due to diseases such as lymphoma. additionally, a high appearance rate in patients with non-malignant tumors, particularly patients with chronic hepatitis B, c and primary biliary cirrhosis (PBc), has been reported since the advent of improvements in the performance of ultrasonographic test instruments (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14). The common hepatic arterial lymph node (no.…”

“…The common hepatic arterial lymph node (no. 8 ln) appearance rate on ultrasonography was reported to be 77-91% in patients with chronic hepatitis c (cHc) (3)(4)(5)(6)(7)(8)(9)(10)(11)(12), 96% in patients with chronic hepatitis B (cHB) (14) and 74-100% in PBc patients (2,10). additionally, no.…”

Enlarged lymph nodes in porta hepatis: Sonographic sign of chronic hepatitis B and C infections

“…Subjects with HCV infection and normal ALT values were followed up, and the results showed that those with increases in ALT levels had lymph nodes larger than those of subjects with persistently normal ALT levels. 25 Nodal sizes were also positively correlated with viremia 19,22 and could be markers for the virological response in the treatment of chronic hepatitis C. 29,32 However, they may be correlated with serological values that would consequently become controversial. 17,22,24,29 Our study demonstrated that different parameters of nodal size led to different results and that nodal width might be superior to other parameters in terms of representing a lymph node in its reactive state.…”