Perihepatitis (Fitz-Hugh-Curtis syndrome)

Ris, Hania W.

doi:10.1016/s0197-0070(84)80131-x

Cited by 24 publications

(7 citation statements)

References 18 publications

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“…This lack of symptomatic presentation may be the result of visiting the ED during or after the recovery phase of PID. A previous study found that symptoms of acute and subacute PID such as fever, abdomen pain, and vaginal discharge are almost always present in patients with FHCS 15. However, in this study, only 15% of patients presented with a fever, and 41% of patients presented with vaginal discharge.…”

Section: Discussioncontrasting

confidence: 69%

Clinical Features of Fitz-Hugh-Curtis Syndrome in the Emergency Department

et al. 2012

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Purpose Fitz-Hugh-Curtis Syndrome (FHCS) is a clinical entity characterized by inflammation of the liver capsule associated with genital tract infection. The aim of this study is to provide physicians with clinical suggestions for diagnostic approaches based on a series of patients who were diagnosed with FHCS. Materials and Methods We conducted a retrospective study of patients who were diagnosed with FHCS after presenting to the emergency department (ED). The symptoms, physical examinations, laboratory findings, radiological findings, and progress of the patients were reviewed. Results During the four-year study period, a total of 82 female patients received a final diagnosis of FHCS in the ED. Chlamydia trachomatis was identified as a pathogen in 89% of the patients. Their clinical characteristics and laboratory findings were described. Fifty-two patients (63.4%) were admitted to the hospital. All of the admitted patients improved after treatment combining antibiotic therapy with conservative care. Conclusion FHCS should be considered as a differential diagnosis for female patients of childbearing age with right upper abdominal pain. Timely diagnosis using biphasic computed tomography (CT) with arterial and portal phases may help ensure adequate medical treatment as well as avoid invasive procedures.

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Section: Discussioncontrasting

confidence: 69%

Clinical Features of Fitz-Hugh-Curtis Syndrome in the Emergency Department

et al. 2012

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“…Symptoms of acute or subacute PID (fever, abdominal pain, vaginal discharge) are almost always present. 29 Right upper quadrant pain. The perihepatic component usually presents as sharp pleuritic pain localized to the right upper quadrant at the lower rib margin, likely relat-Most experts now believe C trachomatis is the culprit more often than N gonorrhoeae ed to inflammation of the underside of the diaphragm.…”

Section: Symptomsmentioning

confidence: 99%

Fitz-Hugh-Curtis syndrome: a diagnosis to consider in women with right upper quadrant pain.

Peter

Jaeger

2004

Cleveland Clinic Journal of Medicine

123

107

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ITZ-HUGH-CURTIS SYNDROME-perihepatitis associated with pelvic inflammatory disease-can pose a diagnostic challenge to the clinician, especially when right upper quadrant pain predominates, mimicking acute gall bladder disease. This article reviews the etiology, pathogenesis, diagnosis, and treatment of this syndrome. s HISTORICAL PERSPECTIVE Association with gonorrhea Fitz-Hugh-Curtis syndrome was first described in 1920 by Carlos Stajano, 1 who noted adhesions between the liver capsule and anterior abdominal wall in patients with gonococcal infection and right upper quadrant pain. In the 1930s Thomas Fitz-Hugh and Arthur Curtis also described the syndrome and made the connection between the acute clinical syndrome of right upper quadrant pain following a pelvic infection and the "violinstring" adhesions found in women with evidence of prior salpingitis. 2,3 Curtis described several cases of these very typical adhesions between the liver and the abdominal wall in patients with gonococcal disease and noted that similar adhesions were not found in other causes of peritonitis, suggesting the combination was a unique syndrome. 4 Fitz-Hugh suggested that Neisseria gonorrhoeae was the cause when he found gram-negative diplococci on smears from the liver capsule in patients with the syndrome. 2 Since then, the diagnosis of Fitz-Hugh-Curtis syndrome has largely been a clinical

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“…The viable and metabolically active EB resides in the macrophages below the synovial lining (Beutler et al, 1994;G erard et al, 1998), and it is estimated that Chlamydia trachomatis is responsible for 35 to 70% of sexually acquired reactive arthritis (Kwiatkowska and Fili-Sosnowska, 2009). Chlamydia trachomatis is also known to cause perihepatitis following pelvic inflammatory disease (Ris, 1984). Evidence for Chlamydia trachomatis crossing the placenta from mother to fetus is supported by the presence of DNA in the chorionic villi and amniotic fluid (Dong et al, 1998) and the cervix among women with a spontaneous abortion (Baud et al, 2011;Ahmadi et al, 2016).…”

Section: Resultsmentioning

confidence: 99%

Chlamydia trachomatis Is Responsible for Lipid Vacuolation in the Amniotic Epithelium of Fetal Gastroschisis

Feldkamp

Pysher

Chambers

2017

Birth Defects Research

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The abnormal amniotic epithelial findings are supported by experimental evidence of the trafficking of host lipids into the chlamydiae inclusion. If not lethal, what harm will elementary bodies inflict to the developing embryo? Do these women have a greater pro-inflammatory response to an environmental exposure, whether cigarette smoking, change in partner, or a pathogen? Testing the hypothesis that Chlamydia trachomatis is responsible for amniotic epithelium vacuoles will be a critical first step. Birth Defects Research 109:1003-1010, 2017. © 2017 Wiley Periodicals, Inc.

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Perihepatitis (Fitz-Hugh-Curtis syndrome)

Cited by 24 publications

References 18 publications

Clinical Features of Fitz-Hugh-Curtis Syndrome in the Emergency Department

Clinical Features of Fitz-Hugh-Curtis Syndrome in the Emergency Department

Fitz-Hugh-Curtis syndrome: a diagnosis to consider in women with right upper quadrant pain.

Chlamydia trachomatis Is Responsible for Lipid Vacuolation in the Amniotic Epithelium of Fetal Gastroschisis

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