2015
DOI: 10.1111/apa.12888
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Perinatal conditions related to growth restriction and inflammation are associated with an increased risk of bronchopulmonary dysplasia

Abstract: Growth restriction and inflammation increased the risk of BPD in preterm infants and prelabour preterm rupture of membranes, small for gestational age, low Apgar score or need for resuscitation should raise clinical suspicions.

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Cited by 98 publications
(78 citation statements)
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“…Pulmonary deterioration was associated with several antecedents and clinical factors at univariate analysis; some of these were reported by previous studies [12,13,14,15,16,17,18,19], while to our knowledge the potential protective role of human milk is a novel finding that needs to be confirmed by other studies. …”
Section: Discussionsupporting
confidence: 60%
See 1 more Smart Citation
“…Pulmonary deterioration was associated with several antecedents and clinical factors at univariate analysis; some of these were reported by previous studies [12,13,14,15,16,17,18,19], while to our knowledge the potential protective role of human milk is a novel finding that needs to be confirmed by other studies. …”
Section: Discussionsupporting
confidence: 60%
“…On the basis of our results, the implementation of antenatal steroid administration and early extubation (resulting in a reduction of endotracheal ventilation on day 7) may have an important role in preventing adverse outcomes. Antenatal steroids have been reported to reduce the incidence of hyaline membrane disease and BPD, even if some researchers did not confirm the protective effect on BPD [18,20,21,22]. …”
Section: Discussionmentioning
confidence: 99%
“…The association between IUGR and BPD has been reported in several groups. [16][17][18] As a risk factor, IUGR is most likely less relevant among NBIs born at an older GA, i.e. more mature infants, given that the latter outcome measure acts as a modifier of this association.…”
Section: Discussionmentioning
confidence: 99%
“…La asociación entre RCIU y DBP ha sido reportada por varios grupos. [16][17][18] Es probable que, como factor de riesgo, la RCIU pierda su preponderancia entre los niños con mayor EG y, por lo tanto, más maduros, al comportarse esta última variable como un modificador de efecto para esta asociación. E x i s t e e v i d e n c i a d e l r o l q u e j u e g a l a inflamación en la patogenia de la DBP.…”
Section: Discussionunclassified