Perinatal outcome of meconium stained amniotic fluid among labouring mothers at teaching referral hospital in urban Ethiopia

Tolu, Lemi Belay; Birara, Malede; Teshome, Tesfalem; Feyissa, Garumma Tolu

doi:10.1371/journal.pone.0242025

Cited by 18 publications

(32 citation statements)

References 11 publications

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“…A similar finding was present in the study conducted by Qadir et al (18.8%) [ 13 ]. In contrast to our study, the incidence of MAS was lower in the study by Tolu et al (6.3%) [ 21 ], whereas a higher incidence of MAS was reported in the study conducted by Shaikh et al (46%) [ 17 ].…”

Section: Discussioncontrasting

confidence: 99%

“…This result was similar to the study conducted by Jain et al [ 14 ] in which early neonatal death was 0.54% in the MSAF group. In contrast to this, there was 9% early neonatal death in the study by Tolu et al [ 21 ]. Neonatal death in MAS was 14.2% in our study, which was similar to a study conducted by Davis et al, in which it was 12% [ 5 ].…”

Section: Discussionmentioning

confidence: 78%

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Impact of Meconium-Stained Amniotic Fluid on Neonatal Outcome in a Tertiary Hospital

Parween¹,

Prasad²,

Poonam³

et al. 2022

Cureus

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Objective The aim of this study was to determine the perinatal outcome of pregnant patients complicated with meconium-stained amniotic fluid (MSAF) compared with clear amniotic fluid. Methodology This prospective cross-sectional study was conducted in the Department of Obstetrics and Gynecology in collaboration with the Department of Pediatrics at Indira Gandhi Institute of Medical Sciences, Patna, India, from September 2016 to January 2018. A total of 200 patients were included in the study after taking their written consent. Out of these 200 patients, 100 patients had MSAF, and the other 100 patients with clear liquor were taken as controls after fulfilling the inclusion and exclusion criteria. These two groups of patients were compared regarding various maternal and neonatal parameters. These parameters were compared and tested statistically for significance. Results Among the 100 patients with MSAF, 20 patients had grade 1 meconium (X), 22 patients had grade 2 meconium (Y), and 58 patients had grade 3 meconium (Z). The majority of patients in the MSAF group were primigravida and more than 25 years of age. In addition, 47% of patients in the MSAF group had some associated high-risk factors and 50% of patients had non-reassuring fetal heart rate patterns, and among these, 39 patients had grade 3 MSAF (X). In the MSAF group, 49% of patients had undergone lower segment cesarean section (LSCS), whereas in the non-MSAF group, it was 37%. Also, 30% of babies in the MSAF group and 13% in the non-MSAF group had neonatal intensive care unit (NICU) admission; 22% of babies in the MSAF group and 12% of babies in the non-MSAF group had an adverse neonatal outcome. Meconium aspiration syndrome was present in 14% of the patients in the MSAF group, and among these, two babies had neonatal death and both had severe birth asphyxia. In the non-MSAF group, there was one neonatal death due to neonatal sepsis. However, after statistically analyzing the neonatal outcome in both the groups, there was no statistical difference between the two groups (p<0.001). Conclusion MSAF is associated with increased frequency of operative delivery, poor neonatal outcomes, and increased NICU admission. Management of labor with MSAF requires appropriate intrapartum care with continuous fetal heart rate monitoring, and this can reduce unnecessary cesarean sections in patients with MSAF.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 78%

Impact of Meconium-Stained Amniotic Fluid on Neonatal Outcome in a Tertiary Hospital

Parween¹,

Prasad²,

Poonam³

et al. 2022

Cureus

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“…The presence of meconium amniotic fluid is considered a controversial factor, and its importance is permanently a subject of analysis. It is discussed if it can behave as a marker of fetal non-well-being or a direct factor of greater damage (28,29). Alterations observed during the monitoring of labor have been shown to be a factor significantly associated with the presence of perinatal asphyxia (25).…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Biological and Psychosocial Factors, Risk Behaviors, and Perinatal Asphyxia in a University Hospital: Matched Case–Control Study, Cali, Colombia (2012–2014)

Torres-Muñoz

Fonseca-Pérez

Laurent

2021

Front. Public Health

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Introduction: Perinatal asphyxia is one of the main causes of morbidity and mortality in newborns. It generates high costs, both social and economic, and presents modifiable risk factors.Objective: To determine the biological and psychosocial factors and risk behaviors associated with the development of perinatal asphyxia (Sarnat II-III) in newborns from low socioeconomic status in a tier III university hospital in the city of Cali, Colombia.Materials and Methods: With a case and control design, 216 patients were studied (54 cases/162 controls) (1 case/3 matched controls). The cases were defined as newborns with modified or severe perinatal asphyxia (Sarnat II-III) between 2012 and 2014, with gestational age ≥ 36 weeks, with neurological signs not attributable to other causes, multiorgan compromise, advanced reanimation, and presence of a sentinel event. For the analysis, conditional logistic regression models were developed to evaluate association (OR), considering that the cases and controls had been paired by the birth and gestational age variables.Results: The final model showed that, from the group of biological variables, meconium amniotic fluid was identified as a risk factor (OR 15.28, 95%CI 2.78–83.94). Induction of labor lowered the risk of perinatal asphyxia by 97% (OR 0.03, 95%CI 0.01–0.21), and monitoring of fetal heart rate was associated with lower odds by 99% (OR 0.01, 95%CI 0.00–0.31) of developing perinatal asphyxia in the newborn. Regarding social variables, the lack of social support was identified as a risk factor for the development of perinatal asphyxia (OR 6.44, 95%CI 1.16–35.66); in contrast, secondary education lowered the odds of developing perinatal asphyxia by 85% when compared with pregnant women who only had primary school education (OR 0.15, 95%CI 0.03–0.77).Conclusion: Assessment of biological and psychosocial factors and social support is important in pregnant women to determine the risk of developing perinatal asphyxia in a low-income population.

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“…In a study by Berkus et al, The medium and thick meconium groups had a fundamentally higher hazard, as evidenced by an abnormal fetal heart rate and cord blood vessels with a pH below 7.20 (markers of intrauterine fetal distress) (Chand et al, 2019). In a study by Tolu et al said that meconium-stained amniotic fluid is associated with increased frequency of operative delivery, birth asphyxia, neonatal sepsis, and neonatal intensive care unit admissions compared to clear amniotic fluid (Tolu et al, 2020). From Leonard's research, 320 cases of fetal distress, of which 13.4% or 43 cases were accompanied by meconium in amniotic fluid, showed that there was a lack of significant relationship between fresh meconium in amniotic fluid and fetal distress in the study (Leonard, et al, 2016).…”

Section: Risk Factorsforfetal Distress During Intrauterineinclude (1) Umbilical Cord Wrappingmentioning

confidence: 99%

Risk Factors for Incidence of Intrauterine Fetal Distress in Hospital of Pamekasan

Ma’roef¹

2021

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Fetal distress during intrauterine is related to many factors. Knowing the risk factors will provide an effort to prevent and detect early fetal distress cases. The objective was to determine the risk factors for fetal distress during intrauterine treatment at dr. H. Slamet Martodirdjo Pamekasan. The method used is analytic observational with a cross-sectional method and the sample is simple random sampling. Samples taken were 184 patients in the delivery room dr. H. Slamet Martodirdjo general hospital Pamekasan. Data was taken by observation from patient medical records during 2018. Through this study, 92 patients experienced intrauterine fetal distress. The main risk factors for fetal distress was umbilical cord twists (p: 0.003, OR: 6,857, 95% CI: 1,914-24,572) and protective factors were maternal anemia (p: 0.018, OR: 0.141, 95% CI : 0.028-0.714). There are several risk factors for fetal distress during the intrauterine process at dr. H. Slamet Martodirdjo Pamekasan, the main factor was umbilical cord twisting where pregnant women with umbilical cord twists have a 6 times risk of experiencing fetal distress compared to those who do not.

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Perinatal outcome of meconium stained amniotic fluid among labouring mothers at teaching referral hospital in urban Ethiopia

Cited by 18 publications

References 11 publications

Impact of Meconium-Stained Amniotic Fluid on Neonatal Outcome in a Tertiary Hospital

Impact of Meconium-Stained Amniotic Fluid on Neonatal Outcome in a Tertiary Hospital

Biological and Psychosocial Factors, Risk Behaviors, and Perinatal Asphyxia in a University Hospital: Matched Case–Control Study, Cali, Colombia (2012–2014)

Risk Factors for Incidence of Intrauterine Fetal Distress in Hospital of Pamekasan

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