Perinephric abscess

Gardiner, Robert A.; Gwynne, Raymond A.; Roberts, Sally

doi:10.1111/j.1464-410x.2011.10050.x

Cited by 52 publications

(66 citation statements)

References 4 publications

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“…women was noted, while in previous studies, the male: Female ratio was reported as 1:31:7 [7,18,20] , and a female predominance as high as 91.8% was also observed [16] . Diagnosis of RA or PNA remains challenging because the symptoms can be insidious and obscure [1,2] . Patients with RA may present with fever, chills, flank or abdo minal pain, fatigue, nausea, decreased appetite, weight loss and even persistent hiccups [7,21,22] .…”

Section: Imaging Studiesmentioning

confidence: 99%

“…Perinephric abscess (PNA) is a collection of suppurative material located between Gerota's fascia and the renal capsule [2] . Complications of urinary tract infections (UTIs) and hematogenous seeding from primary infected sites are the common source of infection [2,3] .…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Complications of urinary tract infections (UTIs) and hematogenous seeding from primary infected sites are the common source of infection [2,3] . Additionally, rupture of renal cortical abscess or renal carbuncle can result in the formation of PNA [2] . As a result of its anatomical location and potential to spread, RA is potentially lethal and the prognosis can be poor, especially in immunosuppressed and cache ctic patients [1,4] .…”

Section: Introductionmentioning

confidence: 99%

“…As a result of its anatomical location and potential to spread, RA is potentially lethal and the prognosis can be poor, especially in immunosuppressed and cache ctic patients [1,4] . PNA originates from hematogenous dissemination, and often has an acute presentation with pain and high spiking temperatures [2] , while in most cases, PNA is notoriously silent clinically [2,3] , thereby the diagnosis can be challenging [2] . It is reported that only 35%38% of patients with PNA are correctly diagnosed at the time of admission [5,6] .…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Renal and perinephric abscesses in West China Hospital: 10-year retrospective-descriptive study

Liu

Cheng-cheng

Liu

et al. 2016

WJN

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AIM:To elucidate the clinical, radiological and laboratory profiles of renal abscess (RA) and perinephric abscess (PNA), along with related treatment and outcome. METHODS:Ninety-eight patients diagnosed with RA or PNA using the primary discharge diagnoses identified from the International Statistical Classification of Diseases and Related Health Problems Tenth Edition (ICD-10) codes (RA: N15.101, PNA: N15.102) between September 2004 and December 2014 in West China Hospital were selected. Medical records including patients' characteristics, symptoms and signs, high-risk factors, radiological features, causative microorganisms and antibiotic-resistance profiles, treatment approaches, and clinical outcomes were collected and analyzed. RESULTS:The mean age of the patients was 46.49 years with a male to female ratio of 41:57. Lumbar pain (76.5%) and fever (53.1%) were the most common symptoms. Other symptoms and signs included chills (28.6%), anorexia and vomiting (25.5%), lethargy (10.2%), abdominal pain (11.2%), flank mass (12.2%), flank fistula (2.0%), gross hematuria (7.1%), frequency (14.3%), dysuria (9.2%), pyuria (5.1%) and weight loss (1.0%). Painful percussion of the costovertebral angle (87.8%) was the most common physical finding. The main predisposing factors were lithiasis (48.0%), diabetes mellitus (33.7%) followed by history of urological surgery (16.3%), urinary tract infections (14.3%), renal function impairment (13.3%), liver cirrhosis (2.0%), neurogenic bladder (1.0%), renal cyst (1.0%), hydronephrosis (1.0%), chronic hepatitis B (1.0%), post-discectomy (1.0%) and post-colectomy (1.0%). Ultrasound (US) and computed tomography were the most valuable diagnostic tools and US was recommended as the initial diagnostic imaging choice.Escherichia coli (51.4%), Staphylococcus aureus (10.0%) and Klebsiella pneumoniae (8.6%) were the main causative microorganisms. Intravenous antibiotic Retrospective Study ORIGINAL ARTICLEtherapy was necessary while intervention including surgical and nonsurgical approaches were reserved for larger abscesses, multiple abscesses, PNAs and nonresponders. CONCLUSION:Heightened alertness, prompt diagnosis, and especially proper antibiotics in conjunction with interventional approaches allow a promising clinical outcome of renal and perinephric abscesses.

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