Perineural Optic Nerve Enhancement on Magnetic Resonance Imaging in Giant Cell Arteritis

Liu, Katy C.; Chesnutt, David A.

doi:10.1097/wno.0b013e3182915b77

Cited by 26 publications

(18 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the past, orbital MRI was not done in typical GCA cases as it is mainly diagnosed on clinical grounds. However, there is increasing evidence of abnormal enhancement of the optic nerve in GCA using T1-weighted images with gadolinium 8–10. The optic nerve sheath involvement is prominent in those cases.…”

Section: Discussionmentioning

confidence: 99%

Anterior ischemic optic neuropathy due to biopsy-proven giant cell arteritis in Thai patients

Attaseth¹,

Vanikieti²,

Poonyathalang³

et al. 2015

OPTH

View full text Add to dashboard Cite

Giant cell arteritis is a systemic granulomatous vasculitis affecting medium to large arteries. An arteritic anterior ischemic optic neuropathy is the most common cause of permanent visual loss. Giant cell arteritis is very rare among Asians. We report six patients with biopsy-proven arteritic anterior ischemic optic neuropathy. Demographic data, clinical manifestations, laboratory findings, treatment, and visual outcome are described in detail and compared with Caucasian patients. We found no differences in any clinical features except for sex preference. Moreover, perioptic nerve sheath enhancement was observed in half of our patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Anterior ischemic optic neuropathy due to biopsy-proven giant cell arteritis in Thai patients

Attaseth¹,

Vanikieti²,

Poonyathalang³

et al. 2015

OPTH

View full text Add to dashboard Cite

show abstract

“…Finding 4 may suggest inflammatory, infiltrative, or demyelinating chiasmopathy. 2,5,[7][8][9][10][11][12][18][19][20][21][22] Clinicians should be aware of the radiographic findings in GCA and, although further testing may be required to exclude alternative etiologies, diagnosis and treatment should not be unnecessarily delayed.…”

Section: Optic Chiasmal Enhancement To Our Knowledge Oursmentioning

confidence: 99%

“…Symptoms include headache, jaw claudication, fever, weight loss, polymyalgia rheumatica, and tender temporal artery. [1][2][3] Atypical presentations may delay diagnosis. 2 Diagnosis is confirmed via superficial temporal artery biopsy (TAB) and neuroimaging is not typically necessary, but some patients in the United States frequently undergo these studies before evaluation.…”

Section: Introductionmentioning

confidence: 99%

“…[4][5][6][7][8] Furthermore, MRI abnormalities including T2 hyperintensity, diffusion-weighted imaging restriction, and gadolinium enhancement may occur in GCA-related AION or PION, broadening differential diagnosis. 2,4,[7][8][9][10] Previously described MRI findings, noted in Table 1, include dural and perineural sheath enlargement, sheath and nerve enhancement, and extracranial and intracranial vascular changes.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Magnetic resonance imaging findings in giant cell arteritis

D’Souza

Morgan

Almarzouqi

et al. 2016

Eye

View full text Add to dashboard Cite

PurposeGiant cell arteritis (GCA) is a systemic vasculitis that affects medium-to-large-caliber arteries. Early diagnosis and treatment is essential as involvement of the ophthalmic artery or its branches may cause blindness. Radiographic findings may be variable and non-specific leading to delay in diagnosis. We conducted a review of the literature on neuroimaging findings in GCA and present a retrospective case series from tertiary-care ophthalmic referral centers of three patients with significant neuroimaging findings in biopsy-proven GCA.MethodsRetrospective case series of biopsy-proven GCA cases with neuroimaging findings at the Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital between 2010-2015 were included in this study. Literature search was conducted using Google Scholar and Medline search engines between the years 1970 and 2015.ResultsWe report findings of optic nerve enhancement, optic nerve sheath enhancement, and the first description in the English-language ophthalmic literature, to our knowledge, of chiasmal enhancement in biopsy-proven GCA. We describe four main categories of neuroimaging findings that may be seen in GCA from our series and from past cases in the literature.DiscussionIt is essential that clinicians be aware of the possible radiographic findings in GCA. Appropriate and prompt treatment should not be delayed based upon these findings.

show abstract

“…Optic perineuritis is characterized by inflammation of the optic nerve sheath and may be idiopathic or secondary to systemic disease, including Behçet disease, Crohn's disease, granulomatosis with polyangiitis, giant cell arteritis, sarcoidosis, tuberculosis, syphilis, and metastasis. [6][7][8][9][10][11][12][13] The patient's extensive studies as outlined above did not reveal an etiology.…”

Section: Differential Diagnosismentioning

confidence: 95%

A 45-year-old man with unilateral optic disc edema and vision loss

Jastrzembski

Torun

2019

Digit J Ophthalmol

View full text Add to dashboard Cite

A 45-year-old man was referred to Beth Israel Deaconess Medical Center for evaluation of decreased vision in his left eye of 1 month's duration. He denied pain with eye movement and diplopia. His past medical history included photorefractive keratectomy in both eyes 2 years prior, rosacea, depression, and obesity. He had been seeing his eye doctor frequently for meibomianitis and dry eye syndrome.

show abstract

Perineural Optic Nerve Enhancement on Magnetic Resonance Imaging in Giant Cell Arteritis

Cited by 26 publications

References 9 publications

Anterior ischemic optic neuropathy due to biopsy-proven giant cell arteritis in Thai patients

Anterior ischemic optic neuropathy due to biopsy-proven giant cell arteritis in Thai patients

Magnetic resonance imaging findings in giant cell arteritis

A 45-year-old man with unilateral optic disc edema and vision loss

Contact Info

Product

Resources

About