Abstract:Perineuronal nets (PNNs), specialized extracellular matrix structures that envelop neurons, have recently been recognized as key players in the regulation of metabolism. This review explores the growing body of knowledge concerning PNNs and their role in metabolic control, drawing insights from recent research and relevant studies. The pivotal role of PNNs in the context of energy balance and whole-body blood glucose is examined. The review also highlights novel findings, including the effects of astroglia, mi… Show more
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