Periodic dietary restriction of animal products induces metabolic reprogramming in humans with effects on health
Konstantinos Rouskas,
Ozvan Bocher,
Alexandros Simistiras
et al.
Abstract:Dietary interventions constitute powerful approaches for disease prevention and treatment. However, the molecular mechanisms through which diet affects health remain underexplored in humans. Here, we compare plasma metabolomic and proteomic profiles between dietary states for a unique group of individuals who alternate between omnivory and animal product restriction (APR) for religious reasons. We find that short-term APR is associated with extensive metabolic reprogramming not detected in a control group of c… Show more
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