Periodic focal epileptiform discharges

Tatum, William O.; Feyissa, Anteneh M.; ReFaey, Karim; Grewal, Sanjeet S.; Alvi, Mohammed Ali; Castro-Apolo, Ramiro; Roth, Grayson; Segura-Duran, Ivan; Mahato, Deependra; Ruiz‐Garcia, Henry; Pamias-Portalatin, Eva; Yelvington, Kirsten; Chaichana, Kaisorn L.; Bechtle, Perry S.; Quiñones‐Hinojosa, Alfredo

doi:10.1016/j.clinph.2019.04.718

Cited by 10 publications

(9 citation statements)

References 52 publications

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“…LPDs were recorded when synchronized periodic ECoG discharges with an amplitude of more than 600 to 800 µV appeared on an area of the lateral temporal lobe of more than 10 cm 2 , which is consistent with previous findings. 10,12,13,19 On ECoG, both the SW polyspikes in patient 1 and the PD spike components with various peaks in patient 2 were recorded as monophasic sharp waves on EEG, which reflects a “smearing effect.” 13 In contrast, a subsequent slow wave in patient 1 was clearly recorded on EEG. This was probably based on the fact that cortical potentials are not substantially attenuated on the scalp for components below 15 Hz, while the 15 to 30 Hz components show clear attenuation.…”

Section: Discussionmentioning

confidence: 99%

“…Third, as in our previous reports, [13][14][15] the cortical source area was calculated based on 1 cm 2 per electrode contact, which can overestimate the source area. To minimize this problem, Tatum et al 19 used high-density ECoG electrodes to demonstrate that the minimum area required to capture PDs was 1.5 to 3 cm at a single gyrus during awake craniotomy. Fourth, during chronic subdural electrode recording, it is necessary to recognize that EEG recording conditions are not physiological.…”

Section: Discussionmentioning

confidence: 99%

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Simultaneous Electroencephalographic and Electocorticographic Recordings of Lateralized Periodic Discharges in Temporal Lobe Epilepsy

et al. 2020

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Objective Lateralized periodic discharges (LPDs), which constitute an abnormal electroencephalographic (EEG) pattern, are most often observed in critically ill patients with acute pathological conditions, and are less frequently observed in chronic conditions such as focal epilepsies, including temporal lobe epilepsy (TLE). Here we aim to explore the pathophysiological mechanism of LPD in TLE. Methods We retrospectively selected 3 patients with drug-resistant TLE who simultaneously underwent EEG and electrocorticography (ECoG) and demonstrated LPDs. We analyzed the correlation between the EEG and ECoG findings. Results In patients 1 and 2, LPDs were recorded in the temporal region of the scalp during the interictal periods, when repeated spikes followed by slow waves (spike-and-wave complexes; SWs) and periodic discharges (PDs) with amplitudes of >600 to 800 µV appeared in the lateral temporal lobe over a cortical area of >10 cm2. In patient 3, when the ictal discharges persisted and were confined to the medial temporal lobe, repeated SWs were provoked on the lateral temporal lobe. When repeated SWs with amplitudes of >800 µV appeared in an area of the lateral temporal lobe of >10 cm2, the corresponding EEG discharges appeared on the temporal scalp. Conclusions LPDs in patients with TLE originate from repeated SWs and PDs of the lateral temporal lobe, which might represent a highly irritable state of the lateral temporal cortex during both interictal and ictal periods.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Simultaneous Electroencephalographic and Electocorticographic Recordings of Lateralized Periodic Discharges in Temporal Lobe Epilepsy

et al. 2020

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“…Nossek et al also report failure rates of awake ECS, with one case series reporting 12.6% experiencing intraoperative seizures and 2.3% failing due to these seizures, and in another series, they report an overall failure rate of 6.4% for awake craniotomy, with 2.1% failing due to seizures, and 4.2% falling due to lack of communication during the mapping . In a retrospective analysis, Tatum et al reported that 5.7% of patients had seizures during ECS . The seizure rate in this report (14.08%) differs from those reported in previous studies, but this includes both aborted/failed ECS as well as limited/incomplete ECS mapping, as we included two cases in which ECS was planned but not attempted due to a generalized seizure occurring prior to ECS deployment.…”

Section: Discussionmentioning

confidence: 53%

“…39,40 In a retrospective analysis, Tatum et al reported that 5.7% of patients had seizures during ECS. 41 The seizure rate in this report (…”

Section: Ecs Failure Ratesmentioning

confidence: 68%

“…39,40 In a retrospective analysis, Tatum et al reported that 5.7% of patients had seizures during ECS. 41 The seizure rate in this report (14.08%) differs from those reported in previous studies, but this includes both aborted/failed ECS as well as limited/incomplete ECS mapping, as we included two cases in which ECS was planned but not attempted due to a generalized seizure occurring prior to ECS deployment. Standard techniques were used for all patients with ECS mapping reported in this study; 5 however, multiple surgeons performed the procedures and it is unclear if this contributed to the seizure rate.…”

Section: Ecs Failure Ratesmentioning

confidence: 81%

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Intraoperative Use of Functional MRI for Surgical Decision Making after Limited or Infeasible Electrocortical Stimulation Mapping

Rigolo

Essayed

Tie

et al. 2019

Journal of Neuroimaging

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BACKGROUND AND PURPOSE Functional magnetic resonance imaging (fMRI) is becoming widely recognized as a key component of preoperative neurosurgical planning, although intraoperative electrocortical stimulation (ECS) is considered the gold standard surgical brain mapping method. However, acquiring and interpreting ECS results can sometimes be challenging. This retrospective study assesses whether intraoperative availability of fMRI impacted surgical decision‐making when ECS was problematic or unobtainable. METHODS Records were reviewed for 191 patients who underwent presurgical fMRI with fMRI loaded into the neuronavigation system. Four patients were excluded as a bur‐hole biopsy was performed. Imaging was acquired at 3 Tesla and analyzed using the general linear model with significantly activated pixels determined via individually determined thresholds. fMRI maps were displayed intraoperatively via commercial neuronavigation systems. RESULTS Seventy‐one cases were planned ECS; however, 18 (25.35%) of these procedures were either not attempted or aborted/limited due to: seizure (10), patient difficulty cooperating with the ECS mapping (4), scarring/limited dural opening (3), or dural bleeding (1). In all aborted/limited ECS cases, the surgeon continued surgery using fMRI to guide surgical decision‐making. There was no significant difference in the incidence of postoperative deficits between cases with completed ECS and those with limited/aborted ECS. CONCLUSIONS Preoperative fMRI allowed for continuation of surgery in over one‐fourth of patients in which planned ECS was incomplete or impossible, without a significantly different incidence of postoperative deficits compared to the patients with completed ECS. This demonstrates additional value of fMRI beyond presurgical planning, as fMRI data served as a backup method to ECS.

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Mapping the Brain During Awake Surgery for Patients with Neurological Disorders Including Brain Tumors

Ruiz‐Garcia

Middlebrooks

Sabsevitz

et al. 2020

Principles of Neuro-Oncology

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Periodic focal epileptiform discharges

Cited by 10 publications

References 52 publications

Simultaneous Electroencephalographic and Electocorticographic Recordings of Lateralized Periodic Discharges in Temporal Lobe Epilepsy

Simultaneous Electroencephalographic and Electocorticographic Recordings of Lateralized Periodic Discharges in Temporal Lobe Epilepsy

Intraoperative Use of Functional MRI for Surgical Decision Making after Limited or Infeasible Electrocortical Stimulation Mapping

Mapping the Brain During Awake Surgery for Patients with Neurological Disorders Including Brain Tumors

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