Periodic leg movements in Cheyne–Stokes respiration

Manconi, Mauro; Vitale, Giovanni; Ferri, Raffaele; Zucconi, Marco; Ferini‐Strambi, Luigi

doi:10.1183/09031936.00163507

Cited by 21 publications

(10 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It could be hypothesized that RLS is associated only with the more severe cases of OSA that are better predicted by neck circumference, as previously suggested [34]. An association between periodic leg movements and respiratory abnormalities during sleep [35] and the significant role of sympathetic activation in periodic leg movements, a condition associated with RLS, have been previously reported [36]. As expected, in this series, quality of sleep was worse in patients with RLS.…”

Section: Discussionsupporting

confidence: 81%

Clinical outcome after acute ischaemic stroke: the influence of restless legs syndrome

Medeiros

Bruin

Paiva

et al. 2010

Euro J of Neurology

View full text Add to dashboard Cite

Background and purpose: The objective was to evaluate the presence of Restless Legs Syndrome (RLS) in acute stroke, its association with sleep disturbances and clinical outcome during long-term follow-up. Methods: This was a longitudinal study (N = 96, 59 men, mean age 64.0 ± 8.9) of cases with acute ischaemic stroke. Patients were asked about the occurrence of RLS symptoms before the cerebrovascular event. RLS was diagnosed using the criteria established by the International RLS Study Group. Stroke outcome was estimated by the Barthel Index and the modified Rankin Scale. Daytime somnolence (Epworth Sleepiness Scale -ESS > 10), poor sleep quality (Pittsburgh Sleep Quality Index -PSQI > 5) and risk of obstructive sleep apnea (OSA) (Berlin questionnaire) were evaluated. Results: Twelve patients (12.5%) met the diagnostic criteria for RLS. All cases had symptoms of RLS before stroke. However, none of the cases had a previous medical diagnosis of RLS or were on use of specific medication. In only one case, a family history of RLS was found. In all patients, RLS symptoms started after the age of 40 (mean age 64 ± 6.7). Daytime sleepiness (44.8%) and poor quality sleep (62.8%) were present. Patients with RLS (12.5%) presented greater neck circumference (P = 0.04) and worse sleep quality (P = 0.007). Risk of OSA (56.2%) was associated with hypertension [OR = 0.12; CI=0.03-0.42]. Stroke outcome was significantly worse at three and 12 months (ANCOVA, P < 0.005) in patients with RLS, remaining after adjustment for diabetes and body mass index (P < 0.05). Conclusions: Patients with acute stroke and RLS have worse clinical outcome, at three and 12 months of follow-up.

show abstract

Section: Discussionsupporting

confidence: 81%

Clinical outcome after acute ischaemic stroke: the influence of restless legs syndrome

Medeiros

Bruin

Paiva

et al. 2010

Euro J of Neurology

View full text Add to dashboard Cite

show abstract

“…This deficit in striatal dopamine receptor in obese people could contribute to the observed link between RLS and OSA as most OSA patients are obese. However, other studies 40 have reported that dopamine agonists do not impact the number of PLMS associated with Cheyne‐Stokes breathing, suggesting that primary dopaminergic dysfunction may not play a major role in their physiopathology. In summary, the physiopathology of RLS/PLMS in sleep‐disordered breathing appears to be heterogeneous and complex.…”

Section: Rls/plms and Sleep‐related Breathing Disordersmentioning

confidence: 89%

Restless legs syndrome: Impact on sleep‐related breathing disorders

Roux

2013

Respirology

View full text Add to dashboard Cite

show abstract

“…In OSAS patients leg movements typically occur synchronously with breathing resumption at the end of each apnea and CPAP treatment is able to decrease PLMS [141]. Recently, Manconi et al [142] described a case of association between Cheyne-Stokes Respiration (CSR) and PLMS. The authors reported synchronization between PLMS and hyperventilation episodes and leg movements were improved by CPAP treatment instead of dopaminergic drugs.…”

Section: Plms In Different Age Categories In Patients With Sleep Dismentioning

confidence: 98%

Sleep-related movement disorders

Merlino

Gigli

2011

Neurol Sci

View full text Add to dashboard Cite

Several movement disorders may occur during nocturnal rest disrupting sleep. A part of these complaints is characterized by relatively simple, non-purposeful and usually stereotyped movements. The last version of the International Classification of Sleep Disorders includes these clinical conditions (i.e. restless legs syndrome, periodic limb movement disorder, sleep-related leg cramps, sleep-related bruxism and sleep-related rhythmic movement disorder) under the category entitled sleep-related movement disorders. Moreover, apparently physiological movements (e.g. alternating leg muscle activation and excessive hypnic fragmentary myoclonus) can show a high frequency and severity impairing sleep quality. Clinical and, in specific cases, neurophysiological assessments are required to detect the presence of nocturnal movement complaints. Patients reporting poor sleep due to these abnormal movements should undergo non-pharmacological or pharmacological treatments.

show abstract

Periodic leg movements in Cheyne–Stokes respiration

Cited by 21 publications

References 24 publications

Clinical outcome after acute ischaemic stroke: the influence of restless legs syndrome

Clinical outcome after acute ischaemic stroke: the influence of restless legs syndrome

Restless legs syndrome: Impact on sleep‐related breathing disorders

Sleep-related movement disorders

Contact Info

Product

Resources

About