Periodontal disease and endometriosis: analysis of the National Health and Nutrition Examination Survey

Kavoussi, Shahryar K.; West, Brady T.; Taylor, George W.; Lebovic, Dan I.

doi:10.1016/j.fertnstert.2007.12.075

Cited by 39 publications

(31 citation statements)

References 44 publications

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“…13 Additionally, it has been suggested that PDs-induced gonadotrophin-releasing and luteinizing hormones levels reductions can result in ovulation failure. 14 Previous reports have also exhibited that PDs are associated with significant higher percentage of endometriosis 15 and maternal PDs can affect the effectiveness of infertility therapies and in vitro fertilization success. 16 Reportedly, PDs can also increase a woman's time to conception.…”

Section: Mini Reviewmentioning

confidence: 98%

Periodontal disease and women reproductive health

Jalali¹

2018

MOJWH

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Periodontal diseases (PDs) include a group of inflammatory diseases characterized by periodontium hard and soft tissues destruction leading to host immune response activation. It has been suggested that bacterial infection-induced direct tissue damages along with indirect effects of host immune responses play roles in pathogenesis of PDs. Increasing numbers of reports have provided strong evidence that there is a potential association between maternal PDs and delivery of preterm low birth weight infants. Moreover, having PDs during pregnancy has been linked with an increased risk for preeclampsia. Previous reports have also exhibited that PDs are associated with significant higher percentage of endometriosis and maternal PDs can affect the effectiveness of infertility therapies and in vitro fertilization success. Increased levels of inflammatory mediators including PGE2 and TNF due to lipopolysaccharides production by periodontopathic bacteria have been attributed to adverse pregnancy outcomes. Since PDs may increase the risk of perinatal mortality and developmental disorders as well as infertility treatments failure, oral health promotions through wellorganized strategies should be prioritized particularly in mothers-to-be.

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Section: Mini Reviewmentioning

confidence: 98%

Periodontal disease and women reproductive health

Jalali¹

2018

MOJWH

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“…Endometriosis has been successfully identified a novel geneenvironment interaction (96). Previous studies have described a positive relationship and inverse association between endometriosis risk and social, environmental and biological factors, as well as their interactions (97)(98)(99)(100)(101)(102)(103)(104)(105)(106)(107). (102), body mass index, longchain omega-3 fatty acid consumption (101), and in utero cigarette exposure (108).…”

Section: Epidemiologymentioning

confidence: 99%

Understanding the role of epigenomic, genomic and genetic alterations in the development of endometriosis (Review)

Kobayashi

Imanaka

Nakamura

et al. 2014

Molecular Medicine Reports

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Endometriosis is a complex disease influenced by genetic, epigenetic and environmental factors. The aim of the present study was to describe genomic instability, genetic polymorphisms and their haplotype, epigenetic alterations associated with predisposition to endometriosis, and the key factors associated with endometriosis-related ovarian neoplasms. Focus has been given on the developing paradigm that epigenetic alterations or genetic mutations in endometriosis may start in utero or in adolescent and young adults. A search was conducted between 1966 and 2010 through the English language literature (online Medline PubMed database) using the keywords endometriosis combined with epigenetic, genetic and environment. Genetic/epigenetic alterations include single‑nucleotide polymorphisms (SNPs), copy number variation, loss of heterozygosity (LOH), and promoter methylation. Several genes with genetic polymorphisms analyzed in the present study tended to overlap previously reported endometriosis susceptibility genes. Retrograde menstruation leads to iron overload, which facilitates the accumulation of somatic mutations through Fenton reaction-mediated oxidative stress. The epigenetic disruption of gene expression plays an important role in the development of endometriosis through interaction with environmental changes. There seems to be at least three spatiotemporally distinct phases of the development of endometriosis: the initial phase of genetic background inherited from parents; followed by epigenetic modifications in the female offspring; and iron overload, which is subject to dynamic modulation later in life. In conclusion, the marked regulation of endometriosis susceptibility genes may stem from a mechanism responsible for epigenetic and genetic mutations based on the microenvironmental changes.

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“…The question which arises is whether the fertility of a woman or a man may be influenced by their oral and in particular their periodontal condition, since the periodontal disease, as a chronic bacterial infection, may be associated directly or indirectly with the presence or establishment of other subclinical infections, which form the causes of infertility [51,52]. The answer to this question is difficult, since there are limited research data, that correlate periodontal disease and periodontitis in particular to the possibility of achieving a pregnancy, in women with infertility problems [65,66] or in situations of men infertility [67,68].…”

Section: Maternal or Paternal Periodontitis And Infertilitymentioning

confidence: 99%

“…Many years later, the relationship of infertility and periodontal disease was re-explored in a cross-sectional survey study of Kavoussi et al [65]. In this study, the researchers investigated the relationship between periodontal disease and endometriosis, using the data of 4,136 women, aged 18-50 years, who were involved in a large multicenter study of the National Health and Nutrition Examination Survey in the years 1999-2004.…”

Section: Maternal or Paternal Periodontitis And Infertilitymentioning

confidence: 99%

Periodontal Disease, Infertility Treatment and In Vitro Fertilization (IVF)

Pavlatou¹,

Dokou²,

Àlex³

et al. 2014

JFIV Reprod Med Genet

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Periodontal disease and particularly periodontitis is a chronic bacterial infection, and belongs, as well as various other acute or subclinical infections, especially of the urogenital system, appendicitis and AbstractIn the last years, research interest has focused on the possible role of maternal periodontitis in the achievement of a pregnancy, as well as the possible role of paternal periodontitis in the success of medication administered for the treatment of infertility. The purpose of this publication is the presentation of the limited number of research data that highlight the relationship between maternal/paternal periodontitis and the effectiveness of fertility treatment.

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Periodontal disease and endometriosis: analysis of the National Health and Nutrition Examination Survey

Cited by 39 publications

References 44 publications

Periodontal disease and women reproductive health

Periodontal disease and women reproductive health

Understanding the role of epigenomic, genomic and genetic alterations in the development of endometriosis (Review)

Periodontal Disease, Infertility Treatment and In Vitro Fertilization (IVF)

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