2020
DOI: 10.1590/1807-3107bor-2020.vol34.0024
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Periodontal disease and its impact on general health in Latin America. Section I: Introduction part I

Abstract: A high level of general and oral health are invaluable assets, a factor not always considered a basic human right for their better life quality. The mouth is a critical point of contact with the external environment, which is established when we talk, chew, swallow and when food digestion begins. From a perspective of the human condition, the mouth is crucial for the integration of sound, social appearance of the individual, and is one of the fundamental components of overall health. Therefore, not having an a… Show more

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Cited by 13 publications
(9 citation statements)
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“…13 However, medical practitioners only had limited knowledge regarding the association between periodontitis and renal, central nervous system, and the respiratory system (21.6, 16.2, and 28.1%, respectively). Additionally, previous research has shown that periodontal diseases may impact an individual's general health or change the course of systemic conditions 14 ( Fig. 6 ).…”
Section: Discussionmentioning
confidence: 98%
“…13 However, medical practitioners only had limited knowledge regarding the association between periodontitis and renal, central nervous system, and the respiratory system (21.6, 16.2, and 28.1%, respectively). Additionally, previous research has shown that periodontal diseases may impact an individual's general health or change the course of systemic conditions 14 ( Fig. 6 ).…”
Section: Discussionmentioning
confidence: 98%
“…It has been largely demonstrated that poor oral health can have a negative effect on general health, consistently impacting daily activities [6][7][8][9][10], so much so that oral health was defined as a Leading Health Indicator 2020 [11].…”
Section: Introductionmentioning
confidence: 99%
“…Portanto, à medida que a população envelhece, o número de pessoas afetadas por doenças periodontais aumentará ainda mais, e sua prevalência irá se concentrar em grupos mais vulneráveis (GAMONAL; BRAVO; MALHEIROS; STEWART et al, 2020)…”
Section: Lista De Figurasunclassified
“…Além disso, o sistema de defesa imune inato do hospedeiro é altamente ativo em tecidos saudáveis e o desequilíbrio na expressão de mediadores inflamatórios contribui de forma significativa para a destruição dos tecidos periodontais (CHAMPAGNE; BUCHANAN; REDDY;PREISSER et al, 2003;DARVEAU, 2010;LARSSON, 2017;PAGE;KORNMAN, 1997;BARTOLD;REYNOLDS, 2020). A magnitude desta resposta imunoinflamatória, em nível celular e molecular, também é ditada pelas características genéticas e epigenéticas do hospedeiro associadas às várias exposições sistêmicas/ambientais, dentre elas tabagismo, estresse, obesidade e hiperglicemia (ALBANDAR; SUSIN; HUGHES, 2018; GAMONAL; BRAVO; MALHEIROS;STEWART et al, 2020;LARSSON, 2017). Uma alteração no padrão epigenético, por exemplo, pode contribuir para as diferenças individuais na expressão gênica local associada à inflamação e suscetibilidade à doença (LARSSON, 2017).Em situação de homeostase, é comum identificar neutrófilos no tecido gengival sem sinais clínicos de inflamação como sangramento ou edema.…”
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