Periodontal disease, smoking, cardiovascular complications and mortality in type 1 diabetes

Khouja, Tumader; Miller, Rachel G.; Moore, Paul A.; Orchard, Trevor J.; Costacou, Tina

doi:10.1016/j.jdiacomp.2019.05.025

Cited by 14 publications

(17 citation statements)

References 47 publications

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“…We did not find a significant association between dental insurance and combined mortality due to CVD, DM, and CBD among those with periodontitis. Previous studies had found an association between periodontitis and mortality due to CVD (Ajwani et al., 2003; DeStefano et al., 1993; Hansen et al., 2016; Jansson et al., 2001; Khouja et al., 2019; Qi et al., 2020; Xu & Lu, 2011), DM (Khouja et al., 2019; Saremi et al., 2005), and CBD (Romandini et al., 2020) separately. The present study combined these specific causes of death as the number of deaths in each specific cause of death was relatively small.…”

Section: Discussionmentioning

confidence: 96%

“…Several studies have shown an association between periodontal pathogens and various systemic diseases (Bale et al., 2017; Bui et al., 2019; Chrysanthakopoulos, 2018; Fiorillo et al., 2019; Inaba & Amano, 2010; Nunn, 2003; Pietropaoli et al., 2019; Sanchez‐Torres et al., 2015). Periodontal disease and its associated products have also been shown to be associated with mortality (Ajwani et al., 2003; Awano et al., 2008; DeStefano et al., 1993; Hansen et al., 2016; Jansson et al., 2002; Khouja et al., 2019; Kim et al., 2013; Qi et al., 2020; Ricardo et al., 2015; Sanchez‐Torres et al., 2015; Saremi et al., 2005; Xu & Lu, 2011; Zhang et al., 2017).…”

Section: Introductionmentioning

confidence: 99%

“…. Periodontal disease and its associated products have also been shown to be associated with mortality (Ajwani et al, 2003;Awano et al, 2008;DeStefano et al, 1993;Hansen et al, 2016;Jansson et al, 2002;Khouja et al, 2019;Kim et al, 2013;Qi et al, 2020;Ricardo et al, 2015;Sanchez-Torres et al, 2015;Saremi et al, 2005;Xu & Lu, 2011;Zhang et al, 2017).…”

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confidence: 99%

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The role of dental insurance in mitigating mortality among working‐age U.S. adults with periodontitis

Sattar

Probst

Merchant

et al. 2020

J Clinic Periodontology

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Periodontitis is a chronic inflammatory disease of the supporting tissues around the teeth caused by infection (Page & Eke, 2007). Studies have shown that periodontitis is associated with various systemic diseases like cardiovascular diseases, obesity, diabetes, cerebrovascular diseases, kidney ailments, Alzheimer's disease, oral/colorectal carcinomas, gastrointestinal diseases, respiratory tract infections, and adverse pregnancy outcomes (Bui et al., 2019;

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Section: Discussionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The role of dental insurance in mitigating mortality among working‐age U.S. adults with periodontitis

Sattar

Probst

Merchant

et al. 2020

J Clinic Periodontology

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show abstract

“…• Periodontitis. El examen odontológico debe considerarse como parte de la evaluación y protección del riesgo de ECV 75 .…”

Section: Otros Factores Consideradosunclassified

Mesa 1: Diabetes mellitus tipo 1 y enfermedad cardiovascular

González¹,

Chertkoff

Burgos

et al. 2020

Rev. Soc. Argent. Diabetes

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La principal causa de muerte en personas con diabetes mellitus tipo 1 (DM1) es de origen cardiovascular (CV). La duración de la DM1 es uno de los predictores más importantes para infarto agudo de miocardio (IAM), junto con el colesterol de lipoproteínas de baja densidad (cLDL) y HbA1c. El desarrollo de DM1 antes de los 10 años de edad se asocia con un riesgo 90 veces mayor de IAM en mujeres. En la DM1 habría una mayor contribución de un estado de inflamación sistémica de bajo de grado.La combinación de electrocardiograma de ejercicio y una técnica de imagen proporciona valor diagnóstico para la detección de isquemia miocárdica y pronóstico. La evaluación del riesgo CV en el adulto mayor debe ser individualizado y categorizarlo según funcionalidad y comorbilidades a fin de fijar objetivos de control de factores glucémicos y no glucémicos personalizados.

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“…Generally, the three DM types are type I diabetes with insulin de iciency, type II diabetes with insulin resistance, and gestational diabetes (Zhang et al, 2019). Hyperglycemia condition will produce diabetic complications, such as cardiovascular diseases (Khouja et al, 2019), chronic kidney disease (Brugnara et al, 2018), blurred vision (Sayin et al, 2015), nephropathy (Elsayed et al, 2019), anxiety and depression (Khalighi et al, 2019), and retinopathy (Gargiulo et al, 2004). Therefore, prevent the occurrence of hyperglycemia condition is an alternative strategy inpatient diabetes management.…”

Section: Introductionmentioning

confidence: 99%

Kinetics of α -glucosidase inhibitory activity and phytochemical analysis of Piper crocatum Ruiz & Pav. leaves ethanol extract

Alfarabi¹,

Bintang²,

Suryani³

et al. 2020

ijrps

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α-Glucosidase is an enzymes group that playing essential roles in the digestion of polysaccharide. Inhibitor of a-glucosidase can decrease polysaccharide digestion rate and therefore plays a significant function in preventing the development of diabetes (type 2). Piper crocatum Ruiz & Pav. is an essential herb applied traditionally in Indonesia to treat diabetes mellitus. This work evaluated the a-glucosidase inhibitory activity of P. crocatum leaves ethanol extract. Phytochemical component of the extract was also analyzed. The α-glucosidase inhibitory activity of the P. crocatum leaves ethanol extract was examined by reacting its different concentrations with α-glucosidase and p-nitrophenyl glucopyranoside. Kinetics of the α-glucosidase inhibition was determined using a Lineweaver-Burke plot. Phytochemical in the extract was determined using GC-MS. Ethanol extract of P. crocatum leaves exhibited moderate α-glucosidase inhibitory activity compared with acarbose. Phytochemical analyses showed the presence of stilbene, linolenic acid, phenol, phytosteroid, and α-tocopherol. The competitive action of P. crocatum leaves ethanol extract is due to its inhibitory effects on α-glucosidase. The stilbene and phenol compounds indicated responsible for anti-diabetic activity from P. crocatum leaves ethanol extract.

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Periodontal disease, smoking, cardiovascular complications and mortality in type 1 diabetes

Cited by 14 publications

References 47 publications

The role of dental insurance in mitigating mortality among working‐age U.S. adults with periodontitis

The role of dental insurance in mitigating mortality among working‐age U.S. adults with periodontitis

Mesa 1: Diabetes mellitus tipo 1 y enfermedad cardiovascular

Kinetics of α -glucosidase inhibitory activity and phytochemical analysis of Piper crocatum Ruiz & Pav. leaves ethanol extract

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