Periodontal manifestations of von Recklinghausen neuro fibromatosis

Shetty, Bhavya; Umesh, Y; Kranti, K; Seshan, Hema

doi:10.4103/0972-124x.113092

Cited by 10 publications

(10 citation statements)

References 8 publications

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“…Neurofibroma is an uncommon benign tumour of the oral cavity derived from the cells that constitute the nerve sheath neurofibromatosis type 1 (NF1), also for about 90% of all cases. Oral cavity involvement by a solitary and peripheral plexiform neurofibroma in patients with no other signs of neurofibromatosis is uncommon [21]. Oral manifestations can be found in almost 72% of NF1 patients [21].…”

Section: Discussionmentioning

confidence: 99%

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Benign tumours and tumour-like lesions in the oral cavity: a retrospective analysis

Błochowiak

Farynowska

Sokalski

et al. 2019

pdia

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Introduction: Oral lesions are divided into non-neoplastic lesions, potentially malignant lesions and neoplastic lesions. More clinical data are needed to determine their helpful clinical pattern. Aim: To present the epidemiological, clinical and histopathological characteristics of the oral lesions. Material and methods: The retrospective study group comprised records of 208 patients which were reviewed according to selected epidemiological and clinical features. All the biopsy specimens were classified into: reactive lesions, precancerous lesions/potentially malignant lesions, salivary gland pathologies, benign and malignant tumours. Results: The lower lip was the most common site involved followed by buccal and vestibular mucosa. The most frequent diagnoses were fibroma, mucocele and papilloma. The predominant pathomorphological forms were nodule and bulla. The most frequent salivary gland pathology was mucocele. Fibroma was the most frequent pathomorphological diagnosis, followed by mucocele and reactive lesions such as irritation fibroma (IF) and granuloma. Conclusions: In cases of oral mucosal lesions, we propose the following algorithm: the exclusion of all odontogenic and iatrogenic causes; the detection and elimination of harmful habits, parafunctions and irritants from the oral cavity especially from the vestibule of the oral cavity and from the lips; all surgical treatment should be performed only after the proper detection and elimination of causative factors to decrease the risk of recurrence; excisional biopsy or in more diffuse lesions incisional biopsy is recommended to confirm clinical diagnosis; and consideration of other factors that can modify the clinical pattern of oral lesions, such as oral hygiene, systemic diseases, and drugs.

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Section: Discussionmentioning

confidence: 99%

“…Oral cavity involvement by a solitary and peripheral plexiform neurofibroma in patients with no other signs of neurofibromatosis is uncommon [21]. Oral manifestations can be found in almost 72% of NF1 patients [21]. NF1 is known as Recklinghausen syndrome.…”

Section: Discussionmentioning

confidence: 99%

Benign tumours and tumour-like lesions in the oral cavity: a retrospective analysis

Błochowiak

Farynowska

Sokalski

et al. 2019

pdia

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“…Neuro broma is an uncommon benign tumour of the oral cavity originating from the nerve sheath, commonly can be found in patients with neuro bromatosis type-1 (NF-1), with an incidence of 72% [35].…”

Section: Neuro Bromamentioning

confidence: 99%

Clinical Features and Management of Oral Nonodontogenic Masses in Children

Zhang¹,

Zhou²,

Shen³

2020

Preprint

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Background: There are numerous clinical reports of oral tumors in children. However, the clinical features and management of oral nonodontogenic masses in children were rare reported. The aim of this article is to present a large series of oral nonodontogenic masses in children, analyzing the clinical characteristics of such masses and reviewing the relevant procedures for treatment.Methods: We conducted an observational retrospective study, reviewing medical records of 171 patients who were treated for oral nonodontogenic masses between 2014 and 2019 at the Department of Pediatric Surgery, Children’s Hospital of Nanjing Medical University. Data collected included age, gender, site, pathologic diagnosis and treatment strategy.Results: All patients were hospitalized in our department. Of the 171 cases, all of them were benign, however, only 1 case diagnosed as inflammatory myofibroblastic tumor showed a malignant process. The most frequent type was hemangioma (63.7%), followed by lymphangioma (16.4%), ranula (7.6%). The most common location of oral masses in the buccal mucosa. The second common location was in tongue. 16 cases of hemangioma were located in two or more sites in cavity. And 29 patients (26.6%) of hemangioma and 11 patients (39.3%) lymphangioma of were found other extraoral lesions. With regard to some cases of hemangioma, the other patients commonly undergone surgical resections or sclerotherapy. The follow-up period ranged from 1 to 5 years. The recurrence rate of hemangioma and lymphangioma were 8.3%, 17.9%, respectively.Conclusion: Most of oral nonodontogenic masses are benign, few oral masses are malignant or mimic a malignant process. Surgical resections are the most common treatment with excellent success.

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“…The attached gingiva is overgrown and sometimes extends to the interproximal gingiva [44]. But, this gingival swelling shows no signs of inflammation [43].…”

Section: Periodontal Diseasesmentioning

confidence: 99%

Oral Manifestations of Neurofibromatosis Type 1

Chérifi¹,

Fournier²,

Berdal³

et al. 2019

JCDSA

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Neurofibromatosis type 1 (NF-1) is a common genetic disorder with a highly variable phenotype. The disease affects both proliferation and differentiation of cells of neurectodermal origin. The presence of tumors is very common like benign nodular neurofibromas. Tumors with unclear prognosis may be present like plexiform neurofibromas whose prognosis is more uncertain. While many organs exhibit pathologies, most commonly affected are the nervous system, skin, gastrointestinal tract and heart. Oral abnormalities are also very common: 72% of NF-1 patients exhibit pathologies in oral mucosa, gums, maxillary and temporomandibular joints, and teeth. The incidence of NF-1 and its relationship to the prevalence of caries have been discussed in other researches. It is known that poor oral hygiene plays a key role in the development of periodontal disease and caries. Here we review the oral manifestations of neurofibromatosis type 1 that we illustrate by a patient followed in the center of rare diseases of the hospital Henri Mondor, clinical service in which we work.

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Periodontal manifestations of von Recklinghausen neuro fibromatosis

Cited by 10 publications

References 8 publications

Benign tumours and tumour-like lesions in the oral cavity: a retrospective analysis

Benign tumours and tumour-like lesions in the oral cavity: a retrospective analysis

Clinical Features and Management of Oral Nonodontogenic Masses in Children

Oral Manifestations of Neurofibromatosis Type 1

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