As the mean age of the population is increasing and the current therapeutic concerns is for teeth to be retained. It is now quite common to encounter complex clinical situations like severe tooth-tissue loss, advanced periodontal disease along with significant esthetic concerns. Dentists now a days, not just restore teeth to make them better for functioning, but also cater an increased esthetic concern of the patients.Thus, many a times, patients who present with a complex restoration also require an esthetic rehabilitation. Although periodontal factors do not usually have a direct effect on the survival of fixed prosthesis however a harmony between prosthesis and periodontium remains critical, affecting the longevity, esthetics and to prevent unsatisfactory treatment outcomes. The present article addresses and summarizes the current knowledge of Prosthetic and Periodontic clinical procedures that play a role in any clinician's attempt to create biologically acceptable and aesthetically pleasing long-lasting restorations.