Periodontal regeneration versus extraction and prosthetic replacement of teeth severely compromised by attachment loss to the apex: 5-year results of an ongoing randomized clinical trial

Cortellini, Pierpaolo; Stalpers, Gabrielle; Mollo, Aniello; Tonetti, Maurizio S.

doi:10.1111/j.1600-051x.2011.01768.x

Cited by 85 publications

(107 citation statements)

References 52 publications

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“…Finally, active treatment for all patients in this study was completed by the end of 1994 before newer regenerative products and materials were available. As periodontal regenerative techniques evolve, the prognosis for all teeth, not only molars, will improve 49 . This alone places a greater emphasis on conveying a more accurate prognosis to the patient.…”

Section: Discussionmentioning

confidence: 99%

An Evidenced‐Based Scoring Index to Determine the Periodontal Prognosis on Molars

Miller

McEntire

Marlow

et al. 2014

Journal of Periodontology

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Background This retrospective study evaluated and assigned scores to six prognostic factors and derived a quantitative scoring system used to determine the periodontal prognosis on molar teeth. Methods Data were gathered on 816 molars in 102 patients with moderate to severe periodontitis. The six factors evaluated, age, probing depth, mobility, furcation involvement, smoking, and molar type, were assigned a numerical score based on statistical analysis. The sum of the scores for all factors was used to determine the prognosis score for each molar. Only patients with all first and second molars at the initial examination qualified for the study. All patients were a minimum of 15 years post treatment. Results The post treatment time ranged from 15 to 40 years and averaged 24 years. When the study was completed, 639 molars survived (78%), and of those surviving molars, 566 survived in health (89%). In molars with lower scores (1,2,and 3) the 15-year survival rates ranged from 99% to 96%. For scores 4, 5, 6 the 15 year survival rates ranged was 95% to 90% and for molars with scores of 7, 8, 9, and 10 the survival rates ranged from 86% to 67%. Conclusions Our results indicate that the periodontal prognosis on molars diagnosed with moderate to severe periodontitis can be calculated using an evidence-based scoring system.

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Section: Discussionmentioning

confidence: 99%

An Evidenced‐Based Scoring Index to Determine the Periodontal Prognosis on Molars

Miller

McEntire

Marlow

et al. 2014

Journal of Periodontology

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show abstract

“…The results of the five-year randomized control trial by Cortellini et al [3] concluded that regenerative therapy can be applied at hopeless teeth and has the potential to change their prognosis. Another factor that was considered was the effect of the hopeless teeth on proximal periodontium as in the past it was thought that retaining them would have a deleterious effect on the adjacent teeth.…”

Section: Discussionmentioning

confidence: 97%

Platelet-rich plasma and bi-phasic tri calcium phosphate in the management of periodontally compromised teeth with hopeless prognosis: A case report with six-year follow-up and surgical re-entry

Sundaram

Rao

2014

J Int Clin Dent Res Organ

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“…It could be hypothesized that this heterogeneity may be explained by the fact that some studies used antibiotics (14)(15)(16)24,25,27,29,34) and others did not (10,17,23,26,28,30,35), by the variable surface treatments, inclusion of smokers (10,(14)(15)(16)(17)(23)(24)(25)28,29,34,35), initial depth of defects and number of remaining bone walls, use of placebo gel in some studies (10,15,16,27,34) and not in others (14,17,23-26,28,29,35), differences in methodological quality, in addition to other variables that could influence the results, such as the surgical technique, quality of instrumentation and biofilm control performed by the patients (45).…”

Section: Discussionmentioning

confidence: 99%

Do the Clinical Effects of Enamel Matrix Derivatives in Infrabony Defects Decrease Overtime? A Systematic Review and Meta-Analysis

Zanatta

Souza²,

Pinto

et al. 2013

Braz. Dent. J.

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Previous systematic reviews have demonstrated better results with enamel matrix derivative proteins (EMDP) as compared with open flap debridement (OFD) for the management of infrabony periodontal defects (IPD). The aim of this study was to determine whether these differences vary according to the follow-up and quality of the studies. Cochrane Central Register of Controlled Trials, Medline/PubMed, Lilacs, Embase and Web of Science electronic databases were searched up to August 2013 for randomized clinical trials.Eligible outcomes were changes in probing depth (PD), clinical attachment level (CAL),gingival recession (GR) and bone changes (BC). Studies with follow-up of 12 months showed differences of 0.97 mm (CI95% 0.52 -1.43) and 1.19 mm (CI95% 0.77 -1.60) for PD and CAL, respectively, favorable for EMDP. Studies with follow-up ≥ 24 months presented advantages of 1.11 mm (CI95% 0.74 -1.48) for CAL and 0.83 mm (CI95% 0.19 -1.48) for PD,with use of EMDP. Considering the quality of studies, those with low risk of bias showed lower difference between groups, presenting 0.8 mm (CI95% 0.24-1.36) for CAL, favorable for EMDP and without differences for PS (0.51 mm, CI95% -0.21 -1.23). In conclusion, follow-up time (< or > 2 years) and the risk of bias influence the results of treatment with EMDP in IPD.

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Periodontal regeneration versus extraction and prosthetic replacement of teeth severely compromised by attachment loss to the apex: 5-year results of an ongoing randomized clinical trial

Abstract: Regenerative therapy can be applied at hopeless teeth and has the potential to change their prognosis; it is a suitable alternative to extraction of severely compromised teeth with intra-bony defects to or beyond the root apex.

Cited by 85 publications

References 52 publications

An Evidenced‐Based Scoring Index to Determine the Periodontal Prognosis on Molars

An Evidenced‐Based Scoring Index to Determine the Periodontal Prognosis on Molars

Platelet-rich plasma and bi-phasic tri calcium phosphate in the management of periodontally compromised teeth with hopeless prognosis: A case report with six-year follow-up and surgical re-entry

Do the Clinical Effects of Enamel Matrix Derivatives in Infrabony Defects Decrease Overtime? A Systematic Review and Meta-Analysis

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