Perioperative Brachytherapy for Pretreated Chest Wall Recurrence of Breast Cancer

Abstract

Isolated local chest wall relapse can be effectively controlled by wide surgical excision and perioperative reirradiation with HDR-AL. This technique may represent a treatment alternative to ultraradical surgery, with equal healing probability and a better quality of life. Small-volume irradiation of the postoperative scar can be performed with HDR-AL brachytherapy, and long-term local control can be achieved with a total dose of 30 Gy.

Late Effects and Cosmetic Results of Conventional Versus Hypofractionated Irradiation in Breast-Conserving Therapy

“…Radiotherapy, with curative and palliative intention, is known to be a highly effective and well-tolerated approach in the management of breast cancer [1,6,8,9,13,14,[24][25][26][27][28].…”

Internal Mammary Nodes in Invasive Breast Carcinoma

“…Significant controversy surrounds targeting of the IMNs with RT [1,2,4,6,8,9,12,13,18,19,24,25,[28][29][30][31][32][33]. Recent analysis of patients treated in the Danish randomized trials who received RT to the chest wall and regional lymphatics including IMNs did not show an adverse effect on cardiovascu- [14].…”

Reirradiation of recurrent breast cancer with and without concurrent chemotherapy

“…A case report of a 63-year-old female patient with left ductal breast cancer 13 years after primary treatment (mastectomy, axillary dissection, and 50 Gy postoperative irradiation) was published by Mayer at al. [ 12 ]. Perioperative HDR-AL with Ir-192 was performed with a dose per fraction of 6 Gy to the reference line, two fractions per week, to a total dose of 30 Gy.…”