Perioperative Bromelain Reduces Pain and Swelling and Improves Quality of Life Measures After Mandibular Third Molar Surgery: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Majid, Omer Waleed; Al-Mashhadani, Bashar Adil

doi:10.1016/j.joms.2013.12.035

Cited by 81 publications

(87 citation statements)

References 18 publications

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“…Results obtained from objective testing may differ significantly from the patient’s own subjective perception . Additionally, informing patients of potential complications and of potential impacts on their lifestyles may improve post‐surgical satisfaction.…”

Section: Discussionmentioning

confidence: 99%

“…Surgical removal of impacted third molars is a common procedure in oral and maxillofacial surgery . Since the third molar region contains loose connective tissue largely consisting of blood and lymph vessels, inflammatory complications such as pain, swelling, trismus and alveolitis are generally seen in the immediate post‐operative period . These may have a deleterious impact on patients’ quality of life (QOL) .…”

Section: Introductionmentioning

confidence: 99%

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The influence of flap design on sequelae and quality of life following surgical removal of impacted mandibular third molars: A split‐mouth randomised clinical trial

Kaya

Yavuz

Saruhan

2019

J of Oral Rehabilitation

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Background Surgical removal of impacted mandibular third molar is one of the most frequently performed interventions in oral and maxillofacial surgery. Objectives To compare two different flap designs in terms of sequelae and quality of life following surgical removal of impacted third molars. Methods This prospective, randomised, split‐mouth clinical study involved patients referred for surgical removal of bilateral symmetrical impacted mandibular third molars. Envelope flap and modified triangular flap techniques were used. The effects of flap design on trismus, swelling, wound dehiscence, alveolar osteitis, haematoma, infection and quality of life were evaluated on post‐operative days 3 and 7. Pain levels were assessed on post‐operative days 1, 3 and 7. Results Significant differences were determined between the two groups in terms of trismus, pain and wound dehiscence scores on post‐operative day 3. However, on post‐operative day 7, this difference was observed only in trismus. Statistically significant differences were also determined between the two groups on post‐operative day 3 for social isolation and eating subscale scores as well as total quality of life score. Conclusion Based on the study findings, the modified triangular flap may be superior to the envelope flap in terms of pain, trismus, and wound dehiscence in the first 3 days after impacted third molar surgery and may have a better impact on quality of life during this process.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The influence of flap design on sequelae and quality of life following surgical removal of impacted mandibular third molars: A split‐mouth randomised clinical trial

Kaya

Yavuz

Saruhan

2019

J of Oral Rehabilitation

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“…First, the diclofenac potassium (dissolvable tablets of Emifenac 50 mg) used in this study has rapid onset of action due to its rate of absorption into the body was fast 2,3,12. Early pain relief and function after teeth extraction and deep cavity preparations were achieved.…”

Section: Discussionmentioning

confidence: 99%

Comparison of paracetamol, ibuprofen, and diclofenac potassium for pain relief following dental extractions and deep cavity preparations

Gazal¹,

Al-Samadani²

2017

SMJ

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Objectives:To compare the effectiveness of different oral analgesics for relieving pain and distress in adults following the extraction of teeth and deep cavity preparations under local anesthesia.Methods:This randomized controlled study was conducted between November 2015 and May 2016. One hundred and twenty patients were randomly allocated to 3 groups. Forty patients were in the paracetamol (1 gram) group, 40 in the ibuprofen (400 mg) group and 40 in the diclofenac potassium (50 mg) group. Evaluation of the post extraction and deep cavity preparations pain was made by patients immediately postoperatively, 2, 4 and 6 hours postoperatively on standard 100 mm visual analogue scales (VAS). Furthermore, each patient was observed preoperatively and immediately postoperatively for signs of distress by using a 5 point face scale.Results:There were significant decreases in mean pain VAS scores for diclofenac potassium group compared to paracetamol and ibuprofen groups at 4 hours postoperatively (one-way Analysis of Variance: p=0.0001, p=0.001) and 6 hours postoperatively (p=0.04, p=0.005). Changes in distress scores from the preoperative score to the postoperative score were made using the paired sample t-test. There were significant decreases in distress scores between the preoperative and postoperative scores (p=0.0001).Conclusions:Diclofenac potassium was more effective than paracetamol or ibuprofen for reducing postoperative pain associated with tooth extraction and deep cavity preparation. Patients’ distress levels can be alleviated by using preemptive analgesics.

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“…When taking bromelain tablets before surgery to 4 days after surgery compared with diclofenac sodium tablets started the day before surgery until 4 days after surgery, it was found to have compatible results on the effect of reducing pain and swelling and trismus after third molar removal. 33 This natural supplement may be considered as an alternative to NSAID therapy for improving the postoperative course.…”

Section: The Power Of the Pineapplementioning

confidence: 99%

Best Practices for Management of Pain, Swelling, Nausea, and Vomiting in Dentoalveolar Surgery

Drew¹

2015

Oral and Maxillofacial Surgery Clinics of North America

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Perioperative Bromelain Reduces Pain and Swelling and Improves Quality of Life Measures After Mandibular Third Molar Surgery: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Cited by 81 publications

References 18 publications

The influence of flap design on sequelae and quality of life following surgical removal of impacted mandibular third molars: A split‐mouth randomised clinical trial

The influence of flap design on sequelae and quality of life following surgical removal of impacted mandibular third molars: A split‐mouth randomised clinical trial

Comparison of paracetamol, ibuprofen, and diclofenac potassium for pain relief following dental extractions and deep cavity preparations

Best Practices for Management of Pain, Swelling, Nausea, and Vomiting in Dentoalveolar Surgery

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