“…The optimal solution is combined anaesthesia (sevoflurane 0.8-1 MAC; propofol ≥ 3 mg/kg/h; fentanyl 5-15 µg/kg -cumulative dose; rocuronium 0.6-1.0 mg/kg for intubation, 0.075-0.15 maintenance dose) [36]. Such a protocol of anaesthesia was used in the group of patients undergoing cardiac surgical procedures aged > 75 years, and the duration of post-operative mechanical ventilation was shortened by over 10 h [37].…”