Perioperative High‐dose Oxygen Therapy in Vascular Surgery

Puckridge, Phillip; Saleem, Hafees; Vasudevan, Thodur; Holdaway, Christopher; Ferrar, D

doi:10.1111/j.1445-2197.2007.04089.x

Cited by 11 publications

(6 citation statements)

References 29 publications

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“…Of these, two non‐randomized studies , one non‐comparative study and nine meta‐analyses were excluded. Three studies with no SSI data were also excluded . One trial by Anthony et al was not included because its study group did not involve only high‐concentration oxygen intervention.…”

Section: Resultsmentioning

confidence: 99%

High inspired oxygen versus low inspired oxygen for reducing surgical site infection: a meta‐analysis

Wang

Hong

Liu

et al. 2015

International Wound Journal

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To perform a meta-analysis of published literature to assess the role of high-concentration inspired oxygen in reducing the incidence of surgical site infections (SSIs) following all types of surgery, a comprehensive search for published randomized controlled trials (RCTs) comparing high- with low-concentration inspired oxygen for SSIs was performed. The related data were extracted by two independent authors. The fixed and random effects methods were used to combine data. Twelve RCTs involving 6750 patients were included. Our pooled result found that no significant difference in the incidence of SSIs was observed between the two groups, but there was high statistic heterogeneity across the studies [risk ratio (RR): 0·91; 95% confidence interval (CI): 0·72-1·14; P = 0·40; I = 54%]. The sensitivity analysis revealed the superiority of high-concentration oxygen in decreasing the SSI rate (RR: 0·86; 95% CI: 0·75-0·98; P = 0·02). Moreover, a subgroup analysis of studies with intestinal tract surgery showed that patients experienced less SSI when high-concentration inspired oxygen was administrated (RR: 0·53; 95% CI: 0·37-0·74; P = 0·0003). Our study provided no direct support for high-concentration inspired oxygen in reducing the incidence of SSIs in patients undergoing all types of surgery.

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Section: Resultsmentioning

confidence: 99%

High inspired oxygen versus low inspired oxygen for reducing surgical site infection: a meta‐analysis

Wang

Hong

Liu

et al. 2015

International Wound Journal

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“…Traditionally, the use of 100% oxygen has been advocated to prevent and treat oxygen desaturation during OLV, maximize blood flow to the dependent lung, decrease nausea, improve peripheral oxygenation and decrease wound infections [3 , 4,5], despite the acknowledgement that high FIO 2 can cause absorption atelectasis [6]. However, there is evidence that the lowest possible fraction of inspired oxygen (FIO 2 ) should be delivered to the thoracic patient to prevent oxidative damage and postoperative ALI [7].…”

Section: Hypoxemiamentioning

confidence: 98%

Update on one-lung ventilation: the use of continuous positive airway pressure ventilation and positive end-expiratory pressure ventilation – clinical application

Grichnik

Shaw²

2009

Current Opinion in Anaesthesiology

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“…In other populations, high perioperative FiO 2 has been associated with decreased nausea, improved peripheral oxygenation, and decreased wound infections. 103,104 However, a lower FiO 2 , which allows acceptable oxygenation may be more appropriate. 26 High FiO 2 is associated with absorption atelectasis both intraoperatively and in patients with ARDS.…”

Section: Inspired Oxygenmentioning

confidence: 99%

Appropriate Ventilatory Settings for Thoracic Surgery: Intraoperative and Postoperative

Lytle

Brown

2008

Semin Cardiothorac Vasc Anesth

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Mechanical ventilation of patients undergoing thoracic surgery is often challenging. These patients frequently have significant underlying comorbidities, including cardiopulmonary disease, and often must undergo 1-lung ventilation. Perioperative respiratory complications are common and are multifactorial in etiology. Increasing evidence suggests that mechanical ventilation is associated with, and may even cause, lung damage in both sick and healthy patients. Gas exchange to provide acceptable end-organ oxygenation remains a primary goal but so too is minimization of risks for acute lung injury. Every ventilator strategy is associated with potential beneficial and adverse side effects. Understanding the impact of various ventilation strategies allows clinicians to provide optimal care for patients.

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Perioperative High‐dose Oxygen Therapy in Vascular Surgery

Cited by 11 publications

References 29 publications

High inspired oxygen versus low inspired oxygen for reducing surgical site infection: a meta‐analysis

High inspired oxygen versus low inspired oxygen for reducing surgical site infection: a meta‐analysis

Update on one-lung ventilation: the use of continuous positive airway pressure ventilation and positive end-expiratory pressure ventilation – clinical application

Appropriate Ventilatory Settings for Thoracic Surgery: Intraoperative and Postoperative

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