2024
DOI: 10.3390/cancers16132304
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Perioperative Immunosuppressive Factors during Cancer Surgery: An Updated Review

Lucillia Bezu,
Dilara Akçal Öksüz,
Max Bell
et al.

Abstract: Surgical excision of the primary tumor represents the most frequent and curative procedure for solid malignancies. Compelling evidence suggests that, despite its beneficial effects, surgery may impair immunosurveillance by triggering an immunosuppressive inflammatory stress response and favor recurrence by stimulating minimal residual disease. In addition, many factors interfere with the immune effectors before and after cancer procedures, such as malnutrition, anemia, or subsequent transfusion. Thus, the peri… Show more

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