Perioperative management of a neonate with Cantrell's pentalogy

Rizwan, Mohammad; Kumar, Kanil Ranjith; Dass, Christopher; Parthiban, M

doi:10.4103/ija.ija_341_18

Cited by 3 publications

(6 citation statements)

References 2 publications

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“…Outcome of POC has remained largely dismal. [ 2 5 6 8 ] Both cases in this report survived and have been followed up for 1 year and 3 years postrepair, respectively. This outcome may be due to the “favorable” variants of the composite anomalies and coordinated multidisciplinary approach to treatment.…”

Section: Discussionmentioning

confidence: 80%

“…[ 4 ] Prenatal diagnosis informs the route of delivery and operative intervention in a specialist center. [ 5 6 ] Postnatal diagnosis of POC is clinical; however, the details of composite anomalies are aided with ultrasonography, echocardiography, computerized tomographic scanning, and MRI. [ 3 4 7 ]…”

Section: Discussionmentioning

confidence: 99%

“…This agrees with the varying nature of the syndrome. [ 2 6 8 ] Case 2 in addition had other multiple anomalies.…”

Section: Discussionmentioning

confidence: 99%

“…[ 4 ] Postnatally, repairs could be single or multistaged, immediate, or delayed. [ 4 5 6 7 8 ] Case 1 had a repair at 1 year, whereas case 2 had an immediate repair on the 4 th day of life.…”

Section: Discussionmentioning

confidence: 99%

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Pentalogy of Cantrell

Ugwu

Etukokwu

Modekwe

et al. 2021

Journal of Indian Association of Pediatric Surgeons

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Section: Discussionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 99%

“…This agrees with the varying nature of the syndrome. [ 2 6 8 ] Case 2 in addition had other multiple anomalies.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Pentalogy of Cantrell

Ugwu

Etukokwu

Modekwe

et al. 2021

Journal of Indian Association of Pediatric Surgeons

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“…We cannot rule out the hypothesis that the selection of patients with a previous history of CINV had a different outcome. In fact, a previous study reported that palonosetron was more effective than ondansetron in the prevention of PONV in post-chemotherapy ovarian cancer surgeries (18). History of CINV increases the chance of PONV and reclassifies patients regarding the risk of nausea and vomiting.…”

Section: ' Discussionmentioning

confidence: 99%

Aprepitant plus palonosetron for the prevention of postoperative nausea and vomiting after breast cancer surgery: a double blind, randomized trial

Grigio¹,

Sousa²,

Guimarães³

et al. 2020

Clinics

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To evaluate the addition of a fourth antiemetic intervention in patients at high risk for postoperative nausea and vomiting (PONV). METHODS: High-risk patients (Apfel score 3 or 4) scheduled for unilateral mastectomy were randomly allocated in one of two groups, oral aprepitant (oral aprepitant 80 mg, intravenous dexamethasone 8 mg, and palonosetron 0.075 mg) and oral placebo (oral placebo, intravenous dexamethasone 4 mg, and palonosetron 0.075 mg). Patients and caregivers were blinded to the group assignments. The primary efficacy endpoints included the incidence of nausea and vomiting, and the secondary endpoints included use of rescue antiemetics during a 48-hour postoperative period. ClinicalTrials.gov: NCT02431286. RESULTS: One hundred patients were enrolled in this study and 91 were analyzed, 48 in group A and 43 in group P. No patient presented with nausea or vomiting in the first 2 hours after surgery. From the 2 nd to the 6 th hour, the incidence of PONV was 8.33% in group A and 9.30% in group P. In the first 24 hours, the incidence of PONV was 27.08% in the group A and 20.93% in group P. From the 24 th to the 48 th hour, the incidence of PONV was 8.33% in group A and 13.95% in group P. There were no statistically significant differences in PONV between groups. CONCLUSION: The addition of aprepitant as a third antiemetic resulted in no significant reduction in the incidence of PONV in this population. However, the incidence of PONV was reduced in relation to the general population.

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Surgical treatment of neonatal Cantrell pentalogy: a case report and literature review

Liao¹,

Huang²,

Li³

2023

AME Case Rep

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Background Pentalogy of Cantrell (PC) is a congenital multiple malformation consisting of midline supraumbilical thoracoabdominal wall defects, anterior and pericardial diaphragm defects, lower sternum defects, ectopia cordis and various intracardiac anomalies, that present a distinctive challenge for care-providers and surgeons. Case Description Cases of PC in twin pregnancies is rare. We report a new born infant, weighing 2,400 g, the younger twin. After birth, he was transferred to the Children’s Hospital of Soochow University due to the prenatal echocardiography indicated that he has ventricular septal defect (VSD), atrial septal defect (ASD) and aortic arch hypoplasia. From the appearance, the lower end of sternum is suspiciously missing, the apical beating point is located at the lower edge of the median xiphoid process of sternum, and the upper abdominal muscle below the beating area is defective. He has the clinical and imaging features of complete type of PC. Three surgical operations were performed in the neonatal period, including end-to-side anastomosis of aortic arch under cardiopulmonary bypass (CPB), patch repair of VSD, repair of ASD, ligation of ductus arteriosus, correction of cardiac vascular malformation and repair of chest and abdominal wall defect, and the postoperative recoveries went smoothly. Conclusions PC is a rare congenital dysplasia, and its condition is complex. Our case shows that surgery is an effective treatment method, and the prognosis is related to the complexity of malformations.

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Perioperative management of a neonate with Cantrell's pentalogy

Cited by 3 publications

References 2 publications

Pentalogy of Cantrell

Pentalogy of Cantrell

Aprepitant plus palonosetron for the prevention of postoperative nausea and vomiting after breast cancer surgery: a double blind, randomized trial

Surgical treatment of neonatal Cantrell pentalogy: a case report and literature review

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