Perioperative management of adult living donor liver transplantation: Part 1 – recipients

Sakai, Tetsuro; Ko, Justin Sangwook; Crouch, Cara; Kumar, Sathish S.; Little, Michael; Chae, Min Suk; Ganoza, Armando; Gómez-Salinas, Luís; Humar, Abhi; Kim, Sang Hyun; Koo, Bon‐Nyeo; Rodríguez-Laiz, Gonzalo; Sirianni, Joel; Song, Jae-Kwan; Ullah, Aisha; Hendrickse, Adrian

doi:10.1111/ctr.14667

Cited by 4 publications

(2 citation statements)

References 121 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As per review of the literature, multiple recent guidelines and reviews reaffirm that LDLT recipient medical workup and preoperative testing should be in line with those established for patients receiving deceased donor grafts. 10-13 It seems that it would be consistent to continue similar cardiopulmonary evaluation regardless of the graft size.…”

Section: Preoperative Considerationsmentioning

confidence: 99%

Anesthesia and Critical Care for the Prediction and Prevention for Small-for-size Syndrome: Guidelines from the ILTS-iLDLT-LTSI Consensus Conference

Chadha,

Sakai,

Rajakumar

et al. 2023

Transplantation

Self Cite

View full text Add to dashboard Cite

Background. During the perioperative period of living donor liver transplantation, anesthesiologists and intensivists may encounter patients in receipt of small grafts that puts them at risk of developing small for size syndrome (SFSS). Methods. A scientific committee (106 members from 21 countries) performed an extensive literature review on aspects of SFSS with proposed recommendations. Recommendations underwent a blinded review by an independent expert panel and discussion/voting on the recommendations occurred at a consensus conference organized by the International Liver Transplantation Society, International Living Donor Liver Transplantation Group, and Liver Transplantation Society of India. Results. It was determined that centers with experience in living donor liver transplantation should utilize potential small for size grafts. Higher risk recipients with sarcopenia, cardiopulmonary, and renal dysfunction should receive small for size grafts with caution. In the intraoperative phase, a restrictive fluid strategy should be considered along with routine use of cardiac output monitoring, as well as use of pharmacologic portal flow modulation when appropriate. Postoperatively, these patients can be considered for enhanced recovery and should receive proactive monitoring for SFSS, nutrition optimization, infection prevention, and consideration for early renal replacement therapy for avoidance of graft congestion. Conclusions. Our recommendations provide a framework for the optimal anesthetic and critical care management in the perioperative period for patients with grafts that put them at risk of developing SFSS. There is a significant limitation in the level of evidence for most recommendations. This statement aims to provide guidance for future research in the perioperative management of SFSS.

show abstract

Section: Preoperative Considerationsmentioning

confidence: 99%

Anesthesia and Critical Care for the Prediction and Prevention for Small-for-size Syndrome: Guidelines from the ILTS-iLDLT-LTSI Consensus Conference

Chadha,

Sakai,

Rajakumar

et al. 2023

Transplantation

Self Cite

View full text Add to dashboard Cite

show abstract

“…Although thrombosis is not uncommon, heparin administration remains unusual given the major hemorrhagic risk and depends on the transplanted organ. In pancreatic transplantation, heparin may even be associated with antiplatelet agents [41,42].…”

Section: Ischemia-reperfusion Injury and Thrombo-inflammation In The ...mentioning

confidence: 99%

Tissue Injury Protection: The Other Face of Anticoagulant Treatments in the Context of Ischemia and Reperfusion Injury with a Focus on Transplantation

Carré,

Kerforne,

Hauet

et al. 2023

IJMS

View full text Add to dashboard Cite

Organ transplantation has enhanced the length and quality of life of patients suffering from life-threatening organ failure. Donors deceased after brain death (DBDDs) have been a primary source of organs for transplantation for a long time, but the need to find new strategies to face organ shortages has led to the broadening of the criteria for selecting DBDDs and advancing utilization of donors deceased after circulatory death. These new sources of organs come with an elevated risk of procuring organs of suboptimal quality. Whatever the source of organs for transplant, one constant issue is the occurrence of ischemia–reperfusion (IR) injury. The latter results from the variation of oxygen supply during the sequence of ischemia and reperfusion, from organ procurement to the restoration of blood circulation, triggering many deleterious interdependent processes involving biochemical, immune, vascular and coagulation systems. In this review, we focus on the roles of thrombo-inflammation and coagulation as part of IR injury, and we give an overview of the state of the art and perspectives on anticoagulant therapies in the field of transplantation, discussing benefits and risks and proposing a strategic guide to their use during transplantation procedures.

show abstract

Perioperative clinical practice in liver transplantation: a cross-sectional survey

Carrier,

Vincelette,

Trottier

et al. 2023

Can J Anesth/J Can Anesth

View full text Add to dashboard Cite

Perioperative management of adult living donor liver transplantation: Part 1 – recipients

Cited by 4 publications

References 121 publications

Anesthesia and Critical Care for the Prediction and Prevention for Small-for-size Syndrome: Guidelines from the ILTS-iLDLT-LTSI Consensus Conference

Anesthesia and Critical Care for the Prediction and Prevention for Small-for-size Syndrome: Guidelines from the ILTS-iLDLT-LTSI Consensus Conference

Tissue Injury Protection: The Other Face of Anticoagulant Treatments in the Context of Ischemia and Reperfusion Injury with a Focus on Transplantation

Perioperative clinical practice in liver transplantation: a cross-sectional survey

Contact Info

Product

Resources

About