Perioperative Management of Patient with Factor XI Deficiency Undergoing Total Knee Arthroplasty

Abstract

Factor XI (FXI) deficiency is a rare, inherited bleeding disorder that is typically asymptomatic and presents with unexpected bleeding after surgery or trauma. We present a patient with FXI deficiency that underwent total knee arthroplasty (TKA) under general anesthesia and received peripheral nerve blocks for postoperative analgesia. We also present a review of literature focused on presentation of FXI deficiency in various surgical settings and choices of perioperative anesthetic management. J o u rn al of A n e s th es ia & C li n ic a l Resea rc h