Perioperative management of patients with atrial fibrillation receiving anticoagulant therapy

Omae, T; Koh, Keito; Kumemura, Masateru; Sakuraba, Sonoko; Katsuda, Yosuke

doi:10.1007/s00540-019-02653-1

Cited by 5 publications

(2 citation statements)

References 102 publications

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“…Palabras clave: Anticoagulantes orales de acción directa; Procedimientos perioperatorios; Dabigatran; Rivaroxaban; Estudio Pause desdeñable de publicaciones. Algunas tratan el tema de una forma general sin especificar patologías [13][14][15][16][17][18][19] y otras detallan actuaciones sólo en pacientes con fibrilación auricular 20,21 . No existe ninguna guía que haga recomendaciones específicas para pacientes con ETV.…”

Section: Introductionunclassified

Manejo perioperatorio de los anticoagulantes orales de acción directa en procedimientos invasivos-quirúrgicos programados. Historia de un claroscuro.

NÚÑEZ-FERNÁNDEZ¹,

DÍAZ-PEROMINGO²

2021

Gal. Clin.

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Currently, patients treated with direct-acting oral anticoagulants (DAOAs) are an increasingly frequent population group in our health centres. The management recommendations of these patients, which are going to be subjected to invasive-diagnostic or surgical tests on a scheduled basis, are included in clinical practice guidelines and reviews. However, to date, all guides have the degree of evidence of expert recommendation. Recently with the publication of the PAUSE study the existing recommendations are likely to change. This review refers to different aspects in relation to the perioperative management of patients treated with DAOAs and the existing controversies.

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Section: Introductionunclassified

Manejo perioperatorio de los anticoagulantes orales de acción directa en procedimientos invasivos-quirúrgicos programados. Historia de un claroscuro.

NÚÑEZ-FERNÁNDEZ¹,

DÍAZ-PEROMINGO²

2021

Gal. Clin.

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“…Patients taking DOACs who undergo major emergency surgeries or experience medical trauma may require rapid reversal of the anticoagulant effect to reduce their risk of bleeding due to anticoagulation [9]. For all reversal agents, the benefits of stopping or reducing bleeding must be balanced against the risk of thrombosis while anticoagulation is reversed [10,11].…”

Section: Introductionmentioning

confidence: 99%

Incidence Rates of Bleeding and Emergency Surgery Due to Trauma or Fracture Among Japanese Patients with Non-valvular Atrial Fibrillation Receiving Oral Anticoagulation Therapy

et al. 2020

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Introduction: In patients with nonvalvular atrial fibrillation (NVAF) receiving oral anticoagulants (OACs), reversal of coagulopathy can be achieved with specific reversal drugs such as idarucizumab, which is indicated for use in patients treated with dabigatran for cases of lifethreatening or uncontrolled bleeding or during emergency procedures that may cause serious bleeding. This study examined the incidence rate (IR) of emergency surgeries and major bleeding episodes associated with fractures and trauma in Japanese patients with NVAF receiving OACs.Methods: This retrospective, non-interventional analysis of health insurance claims was conducted using data from 62,888 OAC-naive adult patients with NVAF who initiated dabigatran, warfarin, apixaban, rivaroxaban, or edoxaban between March 2011 and June 2016. The primary endpoint was overall IR of emergency surgery or major bleeding due to fracture or trauma. Results: Overall IR of emergency surgery or major bleeding due to fracture or trauma considering outcomes until OAC discontinuation was 0.489 per 100 patient-years (PY) (95% confidence interval [CI] 0.406-0.572). Considering first OAC exposure only, the IR was 0.483 per 100 PY (95% CI 0.394-0.573). Emergency surgery/major bleeding events due to fracture or trauma was highest in those aged C 75 years (0.611 per 100 PY [95% CI 0.481-0.741]).

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The stability of a novel synthetic peptide-type hemostatic material under digestive enzyme

Kubo

Kobayashi

Yamamoto

et al. 2022

Minimally Invasive Therapy & Allied Technologies

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Perioperative management of patients with atrial fibrillation receiving anticoagulant therapy

Cited by 5 publications

References 102 publications

Manejo perioperatorio de los anticoagulantes orales de acción directa en procedimientos invasivos-quirúrgicos programados. Historia de un claroscuro.

Manejo perioperatorio de los anticoagulantes orales de acción directa en procedimientos invasivos-quirúrgicos programados. Historia de un claroscuro.

Incidence Rates of Bleeding and Emergency Surgery Due to Trauma or Fracture Among Japanese Patients with Non-valvular Atrial Fibrillation Receiving Oral Anticoagulation Therapy

The stability of a novel synthetic peptide-type hemostatic material under digestive enzyme

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