This review article is an invited review by both the Japanese Society for Dialysis Therapy (JSDT) and Japanese Society for Peritoneal Dialysis (JSPD). Automated peritoneal dialysis (APD) using a cycler machine is an alternative choice for patients who are on peritoneal dialysis (PD) for the treatment of end-stage renal disease (ESRD). The main purpose is to allow more free time and an improved quality of life for PD patients versus continuous ambulatory PD (CAPD). However, it remains unclear which modality is a better choice, especially with regard to the induction period of PD, due to a lack of research. When we propose PD therapy to ESRD patients, in addition to the obvious benefit of more free time, we also need to consider the advantages and disadvantages with regard to each patient's medical comorbidities, physical condition, social activities, psychological readiness, and medical economics. In this review, we attempted to determine which method is more advantageous overall, APD or CAPD. In conclusion, it is important to consider the medical, social, physical, and economic aspects for each PD patient as well as patient preference when helping patients choose between APD and CAPD.