Perioperative Monitoring and Management of Complications

Lin, Hui‐Yi

doi:10.1002/9781119672661.ch7

Cited by 2 publications

(4 citation statements)

References 30 publications

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“…Deeper sedation with fewer adverse effects can be achieved by combining azaperone with ketamine and butorphanol [22,29] or azaperone with ketamine and an alpha-2 adrenergic agonist [30]. Susceptible Pietrain pigs were 100% protected against malignant hyperthermia with azaperone at doses of 0.5-2 mg/kg IM [11].…”

Section: Sedation and Premedicationmentioning

confidence: 99%

“…Alfalfa and other types of hay can delay gastric emptying time, which means that vomiting and aspiration may still occur even after a 12-hour fasting period. To avoid this, alfalfa or other forms of hay should be eliminated from their regular diet 2-3 days before general anesthesia [11]. Following the pre-anesthetic physical examination, pigs can be included in a corresponding anesthetic risk classification system according to the American Society of Anesthesiologists (ASA) physical status classification system modified for veterinary medicine, which is a valuable prognostic tool, recommended to identify an increased risk of anesthetic complications and mortality [12,13].…”

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confidence: 99%

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Pig Sedation and Anesthesia for Medical Research

Costea,

Ene,

Pavel

2023

Preprint

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Anesthesia ensures the welfare of the animal, enables safe and effective procedures, and allows accurate data collection [1]. In clinical veterinary practice, proper training and expertise in anesthesia administration and monitoring are essential. Pigs are commonly used in medical and scientific research as models for studying various aspects of human health, physiology, and disease due to their physiological and anatomical similarities to humans [2–4]. Pigs are suitable experimental animals for many surgery techniques because they are similar in size to humans and have a short reproductive cycle. This makes them ideal for research concerning organ transplantation, cardiovascular surgery, and other procedures that require a large animal model. Pigs also have a similar anatomy to humans, which makes them a good choice for studying diseases and developing new treatments [5]. Sedation and premedication should be administered at the lowest dose to be effective with predictable results and reduced adverse effects, to ensure the safety of both the animal and the team involved in the procedure, with a fast onset and optimizing the induction and maintenance of anesthesia. The goal of induction is to achieve a safe and effective level of anesthesia that ensures the patient's safety and facilitates the research. Most of the time, inhalation anesthesia with endotracheal intubation is the ideal choice for maintenance., allowing efficient anesthetic management. The difficulties related to the endotracheal intubation of pigs can be overcome by knowing the anatomical peculiarities related to the species and the multiple methods cited in the literature. Effective analgesia tailored to the specific procedure, the pig's condition, and individual responses to medications should complete the maintenance and recovery protocols, reducing perioperative complications.

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Section: Sedation and Premedicationmentioning

confidence: 99%

mentioning

confidence: 99%

Pig Sedation and Anesthesia for Medical Research

Costea,

Ene,

Pavel

2023

Preprint

View full text Add to dashboard Cite

show abstract

“…Alfalfa and other types of hay can delay gastric emptying time, which means that vomiting and aspiration may still occur even after a 12-h fasting period. To avoid this, alfalfa or other forms of hay should be eliminated from the regular diet 2-3 days before general anesthesia [11]. Piglets, who are prone to hypoglycemia, should be denied suckling for only 1-2 h before anesthetic induction [9].…”

Section: Physical Examinationmentioning

confidence: 99%

“…Deeper sedation with fewer adverse effects can be achieved by combining azaperone with ketamine and butorphanol [22,29] or azaperone with ketamine and an alpha-2 adrenoreceptor agonist [30,40]. Susceptible Pietrain pigs were protected against halothane-induced malignant hyperthermia with azaperone at doses of 0.5-2 mg/kg IM [11,41].…”

Section: Butyrophenonesmentioning

confidence: 99%

Pig Sedation and Anesthesia for Medical Research

Costea,

Ene,

Pavel

2023

Animals

View full text Add to dashboard Cite

In clinical veterinary practice, proper training and expertise in anesthesia administration and monitoring are essential. Pigs are suitable experimental animals for many surgical techniques because they are similar in size to humans and have a short reproductive cycle. This makes them ideal for research concerning organ transplantation, cardiovascular surgery, and other procedures that require a large animal model. Sedation and premedication should be administered at the lowest dose to be effective with predictable results and reduced adverse effects, to ensure the safety of both the animal and the team involved in the procedure, with a fast onset and optimizing the induction and maintenance of anesthesia. The goal of induction is to achieve a safe and effective level of anesthesia that ensures patient safety and facilitates research. Most of the time, inhalation anesthesia with endotracheal intubation is the ideal choice for maintenance of anesthesia. The difficulties related to endotracheal intubation of pigs can be overcome by knowing the anatomical peculiarities. Effective analgesia tailored to the specific procedure, the pig’s condition, and individual responses to medications should complete the maintenance and recovery protocols, reducing perioperative complications.

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Perioperative Monitoring and Management of Complications

Cited by 2 publications

References 30 publications

Pig Sedation and Anesthesia for Medical Research

Pig Sedation and Anesthesia for Medical Research

Pig Sedation and Anesthesia for Medical Research

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