Perioperative mortality and morbidity of hip fractures among COVID-19 infected and non-infected patients: A systematic review and meta-analysis

Trıpathy, Sujit Kumar; Varghese, Paulson; Panigrahi, Sibasish; Panda, Bijnya Birajita; Srinivasan, Anand; Sen, Ramesh Kumar

doi:10.1016/j.cjtee.2021.05.004

Cited by 6 publications

(6 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several reports have documented inferior clinical results in hip fracture patients during the pandemic compared with the pre-pandemic era [6][7][8][9]. Where adequate infrastructural capacity exists, dual-site services are recommended to improve patient care.…”

Section: Discussionmentioning

confidence: 99%

“…A multicentre retrospective study of six trauma centres by the IMPACT-Scot Study Group reported a 30-day mortality of 35.5% in COVID-19-positive patients following an acute hip fracture [21]. Tripathy et al, in a systematic review and meta-analysis, reported similar findings of increased 30-day mortality (32.23% COVID-19 positive vs 8.85% COVID-19 negative) [8]. Despite these poor results, early surgery is recommended for asymptomatic patients [26].…”

Section: Hip Surgery In Covid-19-positive Patientsmentioning

confidence: 91%

“…Elderly patients with hip fractures are especially vulnerable to developing severe coronavirus disease 2019 (COVID-19) illness, and hospital admission increases the risk of nosocomial infection [4,5]. Furthermore, there is compelling evidence that COVID-19-positive patients with hip fractures have higher 30-day mortality rates and increased morbidity compared to COVID-19-negative patients [6][7][8][9]. These findings required a concerted effort to reduce viral transmission and improve clinical outcomes.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Hip Fracture Surgery in Trinidad and Tobago During the COVID-19 Pandemic: An Analysis of Two Patients Treated in the Parallel Healthcare System

Mencia¹,

Moonsie²,

Cruz³

2022

Cureus

View full text Add to dashboard Cite

The rapid spread of the deadly coronavirus disease 2019 (COVID-19) pandemic has fundamentally affected healthcare delivery globally. As governments struggled to preserve life, several approaches to healthcare delivery have emerged. Central to limiting viral transmission is the separation of patients based on their COVID-19 status. Studies have shown that a geographically separate dual-site service is preferable, contingent upon the local infrastructure and circumstances. Despite the restrictions on free movement, most studies indicate that low-energy hip fractures in elderly patients have remained relatively constant throughout the pandemic. Arguably these patients represent the most vulnerable subgroup in society and are susceptible to developing severe COVID-19 respiratory disease.In keeping with global recommendations, the government of Trinidad and Tobago devised a parallel healthcare system to limit the spread of disease. All regional health authorities under the Ministry of Health were at liberty to implement the system in a manner best suited for their particular infrastructure leading to highly variable practices among institutions. This report describes the clinical course of two hip fracture patients treated within the parallel healthcare system at different regional health authorities. Analysis of these cases provides an understanding of the potential risks to patients entering the parallel healthcare system and an insight into preventative measures to improve clinical outcomes.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Hip Surgery In Covid-19-positive Patientsmentioning

confidence: 91%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Hip Fracture Surgery in Trinidad and Tobago During the COVID-19 Pandemic: An Analysis of Two Patients Treated in the Parallel Healthcare System

Mencia¹,

Moonsie²,

Cruz³

2022

Cureus

View full text Add to dashboard Cite

show abstract

“…This is because geriatric patients are more susceptible to adverse clinical outcomes related to COVID-19 infection, and treatment in geriatric patients is more challenging since they tend to face more comorbid conditions and side effects of polypharmacotherapy [16]. In addition, one systematic review showed that COVID-19 infection increases 30-day mortality, inpatient mortality, and ICU admission among elderly hip fracture patients [5].…”

Section: Discussionmentioning

confidence: 99%

“…The mortality rate of patients older than 70 years and infected with COVID-19 is high compared to people at a young age, 33.7% vs. 13.9% [4]. COVID-19 has been shown to increase the Intensive Care Unit (ICU) admissions, length of stay patients in hospital, and mortality, and decrease the survival rate patients [5,6].…”

Section: Introductionmentioning

confidence: 99%

Perioperative Factors Impact on Mortality and Survival Rate of Geriatric Patients Undergoing Surgery in the COVID-19 Pandemic: A Prospective Cohort Study in Indonesia

Rehatta

Chandra

Sari

et al. 2022

JCM

View full text Add to dashboard Cite

Background: The COVID-19 pandemic continues to have an impact on geriatric patients worldwide since geriatrics itself is an age group with a high risk due to declined physiological function and many comorbidities, especially for those who undergo surgery. In this study, we determine the association between perioperative factors with 30-day mortality and a survival rate of geriatric patients undergoing surgery during COVID-19 pandemic. Methods: A prospective cohort study was conducted at 14 central hospitals in Indonesia. The recorded variables were perioperative factors, 30-day mortality, and survival rate. Analyses of associations between variables and 30-day mortality were performed using univariate/multivariable logistic regression, and survival rates were determined with Kaplan–Meier survival analysis. Results: We analyzed 1621 elderly patients. The total number of patients who survived within 30 days of observation was 4.3%. Several perioperative factors were associated with 30-day mortality (p < 0.05) is COVID-19 (OR, 4.34; 95% CI, 1.04–18.07; p = 0.04), CCI > 3 ( odds ratio [OR], 2.33; 95% confidence interval [CI], 1.03–5.26; p = 0.04), emergency surgery (OR, 3.70; 95% CI, 1.96–7.00; p ≤ 0.01), postoperative ICU care (OR, 2.70; 95% CI, 1.32–5.53; p = 0.01), and adverse events (AEs) in the ICU (OR, 3.43; 95% CI, 1.32–8.96; p = 0.01). Aligned with these findings, COVID-19, CCI > 3, and comorbidities have a log-rank p < 0.05. The six comorbidities that have log-rank p < 0.05 are moderate-to-severe renal disease (log-rank p ≤ 0.01), cerebrovascular disease (log-rank p ≤ 0.01), diabetes with chronic complications (log-rank p = 0.03), metastatic solid tumor (log-rank p = 0.02), dementia (log-rank p ≤ 0.01), and rheumatology disease (log-rank p = 0.03). Conclusions: Having at least one of these conditions, such as COVID-19, comorbidities, emergency surgery, postoperative ICU care, or an AE in the ICU were associated with increased mortality in geriatric patients undergoing surgery during the COVID-19 pandemic.

show abstract

Auswirkungen der COVID-19-Pandemie auf den Verlauf von alterstraumatologischen Patienten mit proximaler Femurfraktur

Knauf,

Eschbach,

Bücking

et al. 2023

Unfallchirurgie

View full text Add to dashboard Cite

Perioperative mortality and morbidity of hip fractures among COVID-19 infected and non-infected patients: A systematic review and meta-analysis

Cited by 6 publications

References 39 publications

Hip Fracture Surgery in Trinidad and Tobago During the COVID-19 Pandemic: An Analysis of Two Patients Treated in the Parallel Healthcare System

Hip Fracture Surgery in Trinidad and Tobago During the COVID-19 Pandemic: An Analysis of Two Patients Treated in the Parallel Healthcare System

Perioperative Factors Impact on Mortality and Survival Rate of Geriatric Patients Undergoing Surgery in the COVID-19 Pandemic: A Prospective Cohort Study in Indonesia

Auswirkungen der COVID-19-Pandemie auf den Verlauf von alterstraumatologischen Patienten mit proximaler Femurfraktur

Contact Info

Product

Resources

About