Perioperative myocardial perfusion

Bulte, Carolien S. E.; Boer, Christa; Loer, Stephan A.

doi:10.1097/aco.0000000000000145

Cited by 2 publications

(1 citation statement)

References 33 publications

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“…In humans, sevoflurane also did not alter myocardial blood flow; rather, adenosine-induced increments in myocardial perfusion were decreased with sevoflurane (6). Isoflurane thus seems to have vasodilatory effects on coronary arteries, whereas xenon and sevoflurane have minimal effects on myocardial blood flow (5).…”

Section: Effects Of Anesthetics On Myocardial Blood Flow and Cardiovascular Hemodynamicsmentioning

confidence: 92%

Myocardial contrast echocardiography in mice: technical and physiological aspects

Verkaik

Poelgeest

Kwekkeboom

et al. 2018

American Journal of Physiology-Heart and Circulatory Physiology

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Myocardial contrast echocardiography (MCE) offers the opportunity to study myocardial perfusion defects in mice in detail. The value of MCE compared with single-photon emission computed tomography, positron emission tomography, and computed tomography consists of high spatial resolution, the possibility of quantification of blood volume, and relatively low costs. Nevertheless, a number of technical and physiological aspects should be considered to ensure reproducibility among research groups. The aim of this overview is to describe technical aspects of MCE and the physiological parameters that influence myocardial perfusion data obtained with this technique. First, technical aspects of MCE discussed in this technical review are logarithmic compression of ultrasound data by ultrasound systems, saturation of the contrast signal, and acquisition of images during different phases of the cardiac cycle. Second, physiological aspects of myocardial perfusion that are affected by the experimental design are discussed, including the anesthesia regimen, systemic cardiovascular effects of vasoactive agents used, and fluctuations in body temperature that alter myocardial perfusion. When these technical and physiological aspects of MCE are taken into account and adequately standardized, MCE is an easily accessible technique for mice that can be used to study the control of myocardial perfusion by a wide range of factors.

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Section: Effects Of Anesthetics On Myocardial Blood Flow and Cardiovascular Hemodynamicsmentioning

confidence: 92%