Perioperative physiology and pharmacology in the obese small animal patient

Love, Lydia; Cline, Martha G.

doi:10.1111/vaa.12219

Cited by 25 publications

(20 citation statements)

References 135 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In animal species, although lean body mass or species-specific adjusted body weight may be appropriate variables, additional studies to determine excess lean body mass associated with adiposity in small animals would help define body weight-adjusted dosing strategies. 50 In this study, V T was set according to actual body weight, because body weight did not differ between lean and Ob animals and there is no validated body mass index for rats. The PEEP level was set based on the pilot studies in Ob animals; however, we cannot exclude that different results could have been obtained at higher or lower PEEP levels and/or with associated recruitment maneuvers.…”

Section: Inflammation and Oxidative Stress After Propofol And Dexmedementioning

confidence: 99%

The Effects of Short-Term Propofol and Dexmedetomidine on Lung Mechanics, Histology, and Biological Markers in Experimental Obesity

Heil

Santos

et al. 2016

Anesthesia &Amp; Analgesia

View full text Add to dashboard Cite

show abstract

Section: Inflammation and Oxidative Stress After Propofol And Dexmedementioning

confidence: 99%

The Effects of Short-Term Propofol and Dexmedetomidine on Lung Mechanics, Histology, and Biological Markers in Experimental Obesity

Heil

Santos

et al. 2016

Anesthesia &Amp; Analgesia

View full text Add to dashboard Cite

show abstract

“…BCS category is the most widely accepted clinical method which uses visual and palpable characteristics [6]. Several previous studies have demonstrated that obesity in dogs and cats is related to metabolic impairment, musculoskeletal problems, respiratory distress, and cardiovascular disease [1,[7][8][9][10]. A previous echocardiographic study in dogs demonstrated that obesity can induce left ventricular hypertrophy [11].…”

Section: Introductionmentioning

confidence: 99%

Obesity-Induced Heart Rate Variability Impairment and Decreased Systolic Function in Obese Male Dogs

Pongkan

Jitnapakarn

Phetnoi

et al. 2020

Animals

View full text Add to dashboard Cite

Obesity can induce cardiovascular diseases in both humans and animals. Heart rate variability (HRV) is an indicator of sympathovagal balance and is used to identify cardiovascular diseases in humans. However, HRV and cardiac function have rarely been investigated in obese dogs. This study investigated the effect of obesity on oxidative stress, HRV, and cardiac function in obese and non-obese dogs. The nine-scale body condition score (BCS) system was used to determine obesity. Thirty small breed dogs were divided into a normal weight group (n = 15) and an obese group (n = 15). All dogs underwent physical examination, plasma malondialdehyde (MDA) measurement, electrocardiography, echocardiography, and two hours of Holter monitoring. This study found that obese dogs had increased plasma MDA and sympathovagal imbalance, which was indicated by impaired time and frequency domains compared to normal weight dogs. Although cardiac function was within normal limits, the echocardiographic study found that the obese dogs had reduced cardiac wall thickness and lower systolic function, as indicated by a reduction in %ejection fraction, %fractional shortening, increased left ventricular (LV) internal diameter during systole, and LV end-systolic volume compared to normal weight dogs. This study concluded that obesity in dogs can induce increased plasma oxidative stress, impaired HRV, and reduced cardiac systolic function compared to non-obese dogs.

show abstract

“…Altered organ function in obese patients is common and predisposes to clinical signs such as hypertension, hypoventilation and hypoxaemia. These can all be particularly life threatening when undergoing anaesthesia and may further predispose to an increased risk of perianaesthetic mortality (Brodbelt 2009, Love 2015).…”

Section: Performing Thorough Preanaesthetic Assessments In Dogs and Catsmentioning

confidence: 99%

Preanaesthetic screening in dogs and cats

Ferreira¹

2020

In Practice

View full text Add to dashboard Cite

Background: Preparation before performing general anaesthesia is essential. In order to comprehensively plan and execute safe anaesthesia, it is vital to quantify anaesthetic risk. However, currently there is limited veterinary literature that collates anaesthetic-related, patient-related and procedural-related risks.Aim of the article: This article highlights previously reported perioperative factors contributing to morbidity and mortality in small animals, as well as important considerations to factor in based on the patient history and findings on clinical examination. It also discusses the current opinions on blood screening and diagnostic imaging.

show abstract

Perioperative physiology and pharmacology in the obese small animal patient

Cited by 25 publications

References 135 publications

The Effects of Short-Term Propofol and Dexmedetomidine on Lung Mechanics, Histology, and Biological Markers in Experimental Obesity

The Effects of Short-Term Propofol and Dexmedetomidine on Lung Mechanics, Histology, and Biological Markers in Experimental Obesity

Obesity-Induced Heart Rate Variability Impairment and Decreased Systolic Function in Obese Male Dogs

Preanaesthetic screening in dogs and cats

Contact Info

Product

Resources

About