Perioperative predictors for complications in patients with Xanthogranulomatous Pyelonephritis treated with nephrectomy

Abstract

Introduction: Xanthogranulomatous pyelonephritis is an inflammatory disease characterized by chronic obstruction and infection. This pathology is a life-threatening condition when surgical treatment is carried out. We decided to retrospectively evaluate whether there were perioperative factors that predict complications in patients who undergo nephrectomy. Methods: We reviewed all nephrectomies done in the period of 2013–2018, in a tertiary referral Hospital with the histopathological diagnosis of Xanthogranulomatous Pyelonephritis. Results: The presence of renal abscess at admission was observed as a risk factor associated with perioperative complications ( p = 0.002), presence of abscess was observed in 47.4% of subjects without complications compared to 89.3% of the perioperative complication group. Higher rates of blood transfusion requirement were observed in the perioperative complication group, 89.3% compared to 68.4% ( p = 0.029), furthermore, perioperative bleeding was slightly greater in the complication group compared to its counterpart, 700 mL, and 600 mL, respectively ( p = 0.01). Conclusions: Anemia and the presence of abscess were important perioperative factors that predict perioperative complications.

Prognostic Factors of Morbimortality in Patients Treated for Xanthogranulomatous Pyelonephritis

“…Montelongo-Rodríguez et al reported that anemia and the presence of renal abscess were associated with major complications. 14 Although anemia and renal abscess were present in our study population, we did not purposefully look for an association between these factors and the occurrence of major complications.…”