2018
DOI: 10.4103/0366-6999.225049
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Perioperative Single-Donor Platelet Apheresis and Red Blood Cell Transfusion Impact on 90-Day and Overall Survival in Living Donor Liver Transplantation

Abstract: Background:Although many previous studies have confirmed that perioperative blood transfusion is associated with poor outcomes after liver transplantation (LT), few studies described the influence of single-donor platelet apheresis transfusion in living donor LT (LDLT). This study aimed to assess the effect of blood products on outcomes for LDLT recipients, focusing on apheresis platelets.Methods:This retrospective study included 126 recipients who underwent their first adult-to-adult LDLT. Twenty-four variabl… Show more

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Cited by 16 publications
(15 citation statements)
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“…[ 69 ] There are high transfusion requirements and transfusion-associated complications. [ 70 71 72 73 74 75 76 77 ] based on in-house blood bank and appropriate facilities for coagulation testing. There is a general awareness regarding the usefulness of POC viscoelastic testing devices.…”
Section: Results Consensus and Discussionmentioning
confidence: 99%
“…[ 69 ] There are high transfusion requirements and transfusion-associated complications. [ 70 71 72 73 74 75 76 77 ] based on in-house blood bank and appropriate facilities for coagulation testing. There is a general awareness regarding the usefulness of POC viscoelastic testing devices.…”
Section: Results Consensus and Discussionmentioning
confidence: 99%
“…The following prognostic scores were also calculated at baseline: CTPs, [7] MELDs, [8,21] MELD-Nas, [9] CLIF-SOFAs, [10] CLIF-C OFs, [11] and COSSH-ACLFs. [19]…”
Section: Methodsmentioning
confidence: 99%
“…Transfusion related immune modulation and risk of infection, neutrophil-mediated exaggerated inflammatory response to tissue damage and ischemia-reperfusion adversely impact outcome following LT. Red cell transfusion is an independent risk factor for early acute kidney injury post liver transplant [27]. Platelet transfusion is a risk factor for acute lung injury, graft injury and correlates strongly with poor post-transplant outcome [22,[28][29][30].…”
Section: Transfusion Of Blood Productsmentioning
confidence: 99%