2021
DOI: 10.1155/2021/5570596
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Perioperative Use of Flurbiprofen Axetil on Renal Function after Transurethral Prostatectomy: A Prospective Randomized Controlled Study

Abstract: Objective. To explore the role of low-dose flurbiprofen axetil in perioperative renal protection. Methods. A total of 83 patients who underwent transurethral resection of the prostate (TURP) between August 2020 and November 2020 at the Third Xiangya Hospital of Central South University were selected, aged 60-85 years old, American Society of Anesthesia (ASA) physical status classes 1-3, BMI 18-30 kg/m2, randomly divided into the experimental group (group F, n … Show more

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“…Even more, a prospective and multicenter study by STARSurg showed that NSAIDs in the postoperative was safer for the patients undergoing gastrointestinal surgery. And the low dose of flurbiprofen axetil (50-100 mg) decrease the rate of AKI after non-cardiac surgery [25,26].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Even more, a prospective and multicenter study by STARSurg showed that NSAIDs in the postoperative was safer for the patients undergoing gastrointestinal surgery. And the low dose of flurbiprofen axetil (50-100 mg) decrease the rate of AKI after non-cardiac surgery [25,26].…”
Section: Discussionmentioning
confidence: 99%
“…But it maybe correlated with decreasing the postoperative kidney inflammatory reaction [33]. High-dose flurbiprofen axetil may destroy the inflammatory balance in the tubules [25]. Besides the clinical studies above, an animal experiment by Takaku indicated that a single dose of parecoxib could reduce the inflammation and tubular renal injury in the rats model of ischemic tubular necrotizing nephritis caused by acute hemorrhagic shock [34].…”
Section: Discussionmentioning
confidence: 99%