Periosteal Chondrosarcoma

Chaabane, Skander; Bouaziz, Mouna Chelli; Drissi, C.; Abid, Leïla; Ladeb, Mohamed Fethi

doi:10.2214/ajr.08.1159

Cited by 59 publications

(50 citation statements)

References 12 publications

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“…12). 10,11 Although myxoid chondrosarcoma may show a ''cordlike'' or whorling growth pattern, it lacks the epithelioid quality of cells and the characteristic adenoid cystic-like areas as observed in ME. 7 In addition, myxoid chondrosarcomas are usually present in middle-aged patients in their 4th or 5th decade while the median age of ME patients is in the 3rd decade.…”

Section: Resultsmentioning

confidence: 99%

Comparison of cytological features of myxopapillary ependymomas on crush preparations

Bradly

Reddy

Cochran

et al. 2009

Diagnostic Cytopathology

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Myxopapillary ependymoma (ME) is a rare neoplasm found predominantly in the sacro-coccygeal region in adults and is characterized by its distinct epithelial and stromal components. From 1990 to April 2008, a total of 10 ME cases were recorded at our institution. Six out of 10 cases underwent frozen section examination with concomitant crush preparations, which forms the basis of this study. The clinical and cytologic findings in all six cases were reviewed. There were four males and two females. The age ranges from 15 to 36 years with a mean age of 27 years. The epithelial component of ME is strikingly similar for all six cases showing tumor cells appearing singly or in loose clusters, most with papillary branching. There was also presence of indistinct cell boundaries, tapered cytoplasmic prolongations, wispy/fragile cytoplasm, and uniform oval-to-fusiform shaped nuclei with an evenly distributed chromatin pattern. The stromal component was composed mainly of thick, metachromatic material and adenoid cystic-like areas. One case showed rosette-like structures. These aforementioned characteristics can be utilized to distinguish ME from other primary and metastatic tumors such as meningioma, adenoid cystic carcinoma, chordoma, mucinous adenocarcinoma, chondrosarcoma, and germ cell tumors.

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Section: Resultsmentioning

confidence: 99%

Comparison of cytological features of myxopapillary ependymomas on crush preparations

Bradly

Reddy

Cochran

et al. 2009

Diagnostic Cytopathology

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“…This tumor accounts for less than 2% of all chondrosarcomas and 0.2% of all bone tumors. 6 Clinically, chondrosarcomas arising in the chest wall present as a palpable mass associated with pain. As the lesion increases in size, symptoms related to compression of abdominal or thoracic organs may dominate the clinical picture.…”

Section: Discussionmentioning

confidence: 99%

“…The underlying cortex shows variable degree of erosion. 4,6 The diagnosis and subclassification of soft tissue and bone tumors in cytology as well as in histology will depend not only on pathological findings but also will rely heavily on clinical and radiological correlation. 8 Consequently, it is crucial to have an experienced bone/soft tissue radiologist evaluating the radiographs.…”

Section: Discussionmentioning

confidence: 99%

“…4 Therefore, without radiological correlation such as size and location of the lesion, the cytological differentiation between these two entities may be virtually impossible in low grade tumors. 6 Enchondroma is a slow-growing, benign cartilaginous tumor that develops in the medullary cavity and typically measures less than 3.0 cm in diameter. It rarely occurs in the ribs.…”

mentioning

confidence: 99%

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Fine‐needle aspiration biopsy diagnosis of costal juxtacortical chondrosarcoma presenting as an abdominal mass

Rosa

Bajestani

Davis

et al. 2010

Diagnostic Cytopathology

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The majority of chondroid tumors arising in the cortex of bone are benign in nature. Juxtacortical chondrosarcoma is a relatively uncommon variant of chondrosarcoma, which by definition, is a malignant cartilaginous tumor that occurs on the surface of bone and measures at least 5 cm. Although the diagnostic value of fine-needle aspiration biopsy is well established, its role in the diagnosis of soft tissue/bone tumors is still not uniformly accepted. Herein, we describe an interesting and controversial case of costal juxtacortical chondrosarcoma presenting as a large intraabdominal mass in a 52-year old female patient, which was diagnosed by fine-needle aspiration biopsy.

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“…In the evaluation of differential diagnoses, extension of an intramedullary chondroid lesion was thought unlikely on the basis of the lack of an associated soft-tissue mass [6]. Juxtacortical lesions, such as juxtacortical chondrosarcoma, periosteal or parosteal osteosarcoma, were considered unlikely on the grounds of the location, the lack of a soft-tissue mass, and the fact that there was no predominance of the extraosseous component, aside from the age of the patient [7][8][9].…”

mentioning

confidence: 99%