Peripartum cardiomyopathy

Jha, Nivedita; Jha, Ajay Kumar

doi:10.1007/s10741-020-10060-y

Cited by 10 publications

(16 citation statements)

References 116 publications

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“…Risk factors for PPCM include multiparity and multiple pregnancies, family history, race, smoking, diabetes, hypertension, pre-eclampsia, malnutrition, and age of the mother ( 4 ). The etiology of PPCM is uncertain.…”

Section: Discussionmentioning

confidence: 99%

“…All women were at least 18 years of age. The study exclusion criteria were as follows: ( 1 ) patients with valvular heart disease, ( 2 ) patients with congenital heart disease, ( 3 ) patients with ischemic cardiomyopathy, ( 4 ) history of malignant tumors and rheumatic diseases. The follow-up duration was at least 6 months after diagnosis of PPCM.…”

Section: Methodsmentioning

confidence: 99%

“…Although clinical manifestations and outcomes of PPCM vary widely, clinical investigations showed that left ventricular (LV) recovery occurred in 23-66% depending on the study size, race, and follow-up duration. In some studies, almost all recovery of left ventricular function occurred within 6 months after diagnosis, and other studies have also reported delayed recovery of left ventricular function (4). There are many studies to explore the predictors of left ventricular recovery in patients with PPCM.…”

Section: Introductionmentioning

confidence: 99%

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Value of the Systemic Immune-Inflammatory Index (SII) in Predicting the Prognosis of Patients With Peripartum Cardiomyopathy

Zhang

Liu

et al. 2022

Front. Cardiovasc. Med.

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BackgroundPeripartum cardiomyopathy (PPCM) is a potentially life-threatening complication of pregnancy. The identification of early prognostic markers in patients diagnosed with PPCM is very important. The systemic immune-inflammation index (SII) is a new inflammatory biomarker, and the aim of this study was to evaluate the prognostic value of SII in patients with PPCM.MethodsA total of 61 patients with PPCM who were admitted in our hospital from 2015 to 2020 were retrospectively analyzed in this study. The follow-up period of all patients was at least 6 months after diagnosis. Recovery of left ventricular (LV) systolic function was defined as the presence of left ventricular ejection fraction > 45%. The second endpoint was defined as composite adverse cardiac events, including cardiac death or hospitalization due to worsening heart failure. Univariate and multivariate logistic regression analysis were used to determine the independent predictors of non-recovery of LV systolic function. The receiver operating characteristic (ROC) curve analysis was used to establish a cut-off level of SII value to predict persistent LV systolic dysfunction.ResultsThe follow-up duration was 40.5 ± 16.3 months. Among the 61 patients, 43 patients showed left ventricular recovery and 18 patients did not at the last follow-up visit. The baseline SII levels were significantly higher in the non-recovery group (P < 0.05). Multivariate logistic regression showed that the SII and left ventricular end-diastolic dimension (LVEDD) were independent predictors of persistent LV systolic dysfunction (OR: 1.177, 95% CI: 1.038–1.335, P = 0.011 and OR: 1.148, 95% CI: 1.011–1.304, P = 0.033, respectively). A SII value of 876 was the best cut-off value (the area under the curve was 0.791, 95% CI: 0.667–0.915, P < 0.05), and the sensitivity and specificity were 73 and 71%, respectively.ConclusionsThe SII and LVEDD are independent prognostic factors for persistent LV systolic dysfunction in patients with PPCM. The SII may be a useful tool for identifying high-risk PPCM patients.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Value of the Systemic Immune-Inflammatory Index (SII) in Predicting the Prognosis of Patients With Peripartum Cardiomyopathy

Zhang

Liu

et al. 2022

Front. Cardiovasc. Med.

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“…Multiparity, advanced maternal age (>30 years old), multiple pregnancies, preeclampsia, gestational hypertension, and women of African ethnicity are potential risk factors [20][21][22][23]. Wang et al suggested that multiparity (> three children), twin pregnancies, preeclampsia, and infrequently other hypertensive illnesses are significant correlations [24].…”

Section: Risk Factors and Etiopathologymentioning

confidence: 99%

“…Long-term tocolysis and African race have also been implicated as determinants [26,[28][29][30]. Selenium and zinc deficiency and substance abuse are other risk factors [22].…”

Section: Risk Factors and Etiopathologymentioning

confidence: 99%

Anesthetic Management in Peripartum Cardiomyopathy: A Contemporary Review

Nayak¹,

Ninave²,

Tayade³

et al. 2022

Cureus

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Peripartum cardiomyopathy (PPCM) is an uncommon disorder of the cardiovascular system and is linked to high rates of morbidity and mortality. It is an idiopathic condition characterized by left ventricular systolic dysfunction with an ejection fraction of approximately 45% near the end of pregnancy or immediately after delivery. Anesthesia management in these women is challenging due to low physiological reserve and potential negative effects on the fetus. To ensure that mother and child are supported safely through delivery, careful anesthesia control is required. Here, in this review article, we discuss the anesthetic implications in preoperative, operative, and postoperative phases in women with perioperative cardiomyopathy undergoing vaginal delivery or cesarean section.

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