Peripheral Ameloblastoma: A Case Report and Review of Literature

Abstract

Peripheral ameloblastoma, a rare and unusual variant of odontogenic tumour, comprises about 2–10% of all ameloblastomas. The extraosseous location is the peculiar feature of this type of tumour, which is otherwise similar to the classical ameloblastoma. This paper describes a case of peripheral ameloblastoma in a 67-year-old female affecting the lingual alveolar mucosa of the mandibular 32–34 region which was clinically diagnosed as pyogenic granuloma. This paper becomes important due to availability of all data, makeing it a well-documented case.

Malignant peripheral ameloblastoma arising from the gingiva: A case report

“…[6] The first-line therapy for peripheral ameloblastomas is conservative supraperiosteal surgical excision with adequate disease-free margins, whereas the first-line therapy for ameloblastic carcinomas is radical surgical excision. [14,18] However, the patient in our case declined surgical excision and will therefore undergo radiation therapy and be followed closely. While a wide range of recurrence rates have been reported for central ameloblastomas based on the extent of the initial resection, the recurrence rate of peripheral ameloblastomas has been reported to be 16%-19%.…”

“…[5] Differential diagnosis includes peripheral giant cell granuloma, peripheral odontogenic fibroma, peripheral ossifying fibroma, papilloma, pyogenic granuloma, epulis, and fibroma. [13][14][15] Radiological examination may demonstrate superficial cortical bone erosion or depression, which are known as "cupping" or "saucerization". [14,15] However, there may not be any radiographic evidence of bone involvement.…”

“…[13][14][15] Radiological examination may demonstrate superficial cortical bone erosion or depression, which are known as "cupping" or "saucerization". [14,15] However, there may not be any radiographic evidence of bone involvement. [14,15] Histological examination would reveal similar characteristics to intraosseous ameloblastomas.…”

“…[14,15] However, there may not be any radiographic evidence of bone involvement. [14,15] Histological examination would reveal similar characteristics to intraosseous ameloblastomas. [16,17] According to the World Health Organization, the histological features of the follicular variant of peripheral ameloblastomas include islands of odontogenic epithelium within a fibrous stroma and peripheral palisading basal cells with vacuolated cytoplasm and hyperchromatic nuclei displaced away from the basement membrane.…”

Extraosseous Ameloblastoma of Maxillary Gingiva- A Case Report

“…Our case even though was measuring 3 cm × 2 cm, the histopathology was typically benign, and the patient is disease free one year after excision. Treated cases of Peripheral ameloblastoma need to be followed for longer period for early detection of recurrence or malignant transformation [14].…”