Ameloblastoma is an epithelial odontogenic tumour of the jaw and exhibits diverse microscopic patterns which occurs either singly or in combination with other patterns. Peripheral ameloblastoma is a rare odontogenic soft tissue tumor, derived from epithelial and/or mesenchymal elements being part of the tooth-forming apparatus. The lesions responsible for approximately 1% to 5% of all cases of ameloblastoma affecting alveolar mucosa and gingiva occurring mainly, in the middle age. This article describes a case of peripheral ameloblastoma affecting a 35-year-old female. The lesion was located in the right buccal space. The occurrence and pathogenesis of peripheral ameloblastomas in general, are reviewed. The tumour was excised and no recurrence has been observed after twenty four months of surgery.