Peripheral Angioplasty as the First-choice Revascularization Procedure in Diabetic Patients with Critical Limb Ischemia: Prospective Study of 993 Consecutive Patients Hospitalized and Followed Between 1999 and 2003

Faglia, Ezio; Paola, Luca Dalla; Clerici, Giacomo; Clerissi, J; Graziani, Lanfroi; Fusaro, Massimiliano; Gabrielli, L.; Losa, Sergio; Stella, Andréa; Gargiulo, Mauro; Mantero, Manuela; Caminiti, Maurizio; Ninkovic, Sasa; Curci, Vincenzo; Morabito, Alberto

doi:10.1016/j.ejvs.2005.02.035

Cited by 353 publications

(263 citation statements)

References 23 publications

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“…Studies on the treatment of PAD in diabetic foot disease are also scarce, and many questions remain to be answered. It is unclear at what degree of peripheral ischaemia intervention is cost-effective and which procedure-bypass or endovascular intervention-should be performed [29,30]. Treatment of infection in patients with PAD is another topic that has gained little attention.…”

Section: Discussionmentioning

confidence: 99%

High prevalence of ischaemia, infection and serious comorbidity in patients with diabetic foot disease in Europe. Baseline results from the Eurodiale study

et al. 2006

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Aims/hypothesis Large clinical studies describing the typical clinical presentation of diabetic foot ulcers are limited and most studies were performed in single centres with the possibility of selection of specific subgroups. The aim of this study was to investigate the characteristics of diabetic patients with a foot ulcer in 14 European hospitals in ten countries.Methods The study population included 1,229 consecutive patients presenting with a new foot ulcer between 1

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Section: Discussionmentioning

confidence: 99%

High prevalence of ischaemia, infection and serious comorbidity in patients with diabetic foot disease in Europe. Baseline results from the Eurodiale study

et al. 2006

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“…It has been reported that PAD is commonly seen in patients on HD (6). In this day and age, PTA has become a common therapeutic standard for PAD in non-HD patients (7,8), and PTA is reported to be effective in patients on HD (9). However, vascular calcification and diffuse lesions may make the PTA procedure difficult to perform (10).…”

mentioning

confidence: 99%

Cilostazol Improves Long-Term Patency after Percutaneous Transluminal Angioplasty in Hemodialysis Patients with Peripheral Artery Disease

Ishii

Kumada

Toriyama

et al. 2008

Clinical Journal of the American Society of Nephrology

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“…The main studies in the literature [13,16,[23][24][25][26][27][28][29][30] reported, for endovascular treatment, a technical success rate of about 90 %, a negligible mortality rate, and a limb salvage rate at 3-5 years of 72-98 %.…”

Section: Discussionmentioning

confidence: 99%

“…The primary goal of PTA treatment is to restore the patency of at least one below-the-knee (BTK) vessel, preferably the tributary of the anatomical region of the ulcer [9]. Several studies have demonstrated good results in terms of patency and limb salvage after endovascular treatment of diabetic foot [10][11][12][13][14]. Many, however, are limited by the presence of a heterogeneous population with different stages of ischemia (claudication, rest pain, trophic lesions) and different treatment modalities, with PTA performed both in the above-the-knee (ATK) and BTK areas [15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Endovascular Treatment of Diabetic Foot in a Selected Population of Patients with Below-the-Knee Disease: Is the Angiosome Model Effective?

Fossaceca

Guzzardi

Cerini

et al. 2013

Cardiovasc Intervent Radiol

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Purpose To evaluate the efficacy of percutaneous transluminal angioplasty (PTA) in a selected population of diabetic patients with below-the-knee (BTK) disease and to analyze the reliability of the angiosome model. Methods We made a retrospective analysis of the results of PTA performed in 201 diabetic patients with BTK-only disease treated at our institute from January 2005 to December 2011. We evaluated the postoperative technical success, and at 1, 6, and 12 months' follow-up, we assessed the rates and values of partial and complete ulcer healing, restenosis, major and minor amputation, limb salvage, and percutaneous oximetry (TcPO 2 ) (Student's t test). We used the angiosome model to compare different clinicolaboratory outcomes in patients treated by direct revascularization (DR) from patients treated with indirect revascularization (IR) technique by Student's t test and the v 2 test. Results At a mean ± standard deviation follow-up of 17.5 ± 12 months, we observed a mortality rate of 3.5 %, a major amputation rate of 9.4 %, and a limb salvage rate of 87 % with a statistically significant increase of TcPO 2 values at follow-up compared to baseline (p \ 0.05). In 34 patients, treatment was performed with the IR technique and in 167 by DR; in both groups, there was a statistically significant increase of TcPO 2 values at follow-up compared to baseline (p \ 0.05), without statistically significant differences in therapeutic efficacy. Conclusion PTA of the BTK-only disease is a safe and effective option. The DR technique is the first treatment option; we believe, however, that IR is similarly effective, with good results over time.

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Peripheral Angioplasty as the First-choice Revascularization Procedure in Diabetic Patients with Critical Limb Ischemia: Prospective Study of 993 Consecutive Patients Hospitalized and Followed Between 1999 and 2003

Abstract: PTA as the first choice revascularisation procedure is feasible, safe and effective for limb salvage in a high percentage of diabetic patients. Clinical restenosis was an infrequent event and PTA could successfully be repeated in most cases.

Cited by 353 publications

References 23 publications

High prevalence of ischaemia, infection and serious comorbidity in patients with diabetic foot disease in Europe. Baseline results from the Eurodiale study

High prevalence of ischaemia, infection and serious comorbidity in patients with diabetic foot disease in Europe. Baseline results from the Eurodiale study

Cilostazol Improves Long-Term Patency after Percutaneous Transluminal Angioplasty in Hemodialysis Patients with Peripheral Artery Disease

Endovascular Treatment of Diabetic Foot in a Selected Population of Patients with Below-the-Knee Disease: Is the Angiosome Model Effective?

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