Peripheral calcifying epithelial odontogenic tumor – Case report

Abstract

The calcifying epithelial odontogenic tumor (CEOT), Pindborg tumor is a benign, slow growing, but locally invasive neoplasm. It is known to have a common intraosseous variant and a very rare extraosseous variant. We report an unusual case of an extraosseous variant of CEOT of unusual large size and maxillary anterior location, the treatment was planned considering the clinical, radiological and histological features. Though peripheral types are less aggressive and had no recurrence, in our case regular follow up is required considering the aggressiveness of the lesion and its proximity to important adjacent structures.

Peripheral Calcifying Epithelial Odontogenic Tumour Mimicking a Gingival Inflammation: A Diagnostic Dilemma

“…Only one case described by Shetty et al (2014) showed an atypical presentation of peripheral CEOT with great dimensions and calcifications and was treated through maxillectomy [4]. Despite these characteristics in the present case as well as elsewhere, there are a few cases with evidence of relapse [1, 4, 8]. …”

“…In a recent literature review, Shetty et al (2014) reported that peripheral CEOT is more common among females in the third and fourth decade of life (mean age of 37.33 years), usually affecting the anterior region of the maxilla [4]. Although the majority of the lesions are unilateral, studies have reported cases of bilateral lesions and tumours in maxilla and mandible simultaneously [2, 8].…”

“…Nevertheless, because of the presence of the gingival variant, other possible origins have been discussed and reported in other studies [4]. As soft tissues are exclusively affected, it has been strongly demonstrated that these tumours can also stem from basal cells of the oral epithelium, which persist in the region following disintegration of epithelial remnants (rests of Serres) [4]. …”

“…Differently from the central variant, the peripheral CEOT is more prevalent in females, occurring between the third and fourth decades of life and involving the anterior maxillary region [4, 5]. These tumours are usually asymptomatic and tend to be less aggressive, causing only alterations in soft tissues.…”

“…These tumours are usually asymptomatic and tend to be less aggressive, causing only alterations in soft tissues. They respond to surgical treatment and do not relapse if properly treated [4]. …”