Peripheral circulation in the newborn: Interaction of peripheral blood flow, blood pressure, blood volume, and blood viscosity

Linderkamp, Otwin; Versmold, H; Strohhacker, I.; Riegel, K; Betke, Klaus

doi:10.1203/00006450-197901000-00078

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“…In infants of 1,000-1,500 g, BP and blood volume correlated significantly only at low (<70 ml/kg) or at high (MOO ml/kg) blood volumes, but in about half of the hypovolemic infants BP was in the normal range (18). In human infants, peripheral resistance decreased with increasing blood volume (19). Central venous pressure (CVP) is more closely related to neonatal blood volume.…”

Section: Blood Volume and Blood Pressurementioning

confidence: 99%

Control of Blood Pressure and the Distribution of Blood Flow

Versmold

1991

Int J Technol Assess Health Care

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Systemic blood pressure (BP) is the product of cardiac output and total peripheral resistance. Cardiac output is controlled by the heart rate, myocardial contractility, preload, and afterload. Vascular resistance (vascular hindrance × viscosity) is under local autoregulation and general neurohumoral control through sympathetic adrenergic innervation and circulating catecholamines. Sympathetic innovation predominates in organs receivingflowin excess of their metabolic demands (skin, splanchnic organs, kidney), while innervation is poor and autoregulation predominates in the brain and heart. The distribution of blood flow depends on the relative resistances of the organ circulations. During stress (hypoxia, low cardiac output), a raise in adrenergic tone and in circulating catecholamines leads to preferential vasoconstriction in highly innervated organs, so that blood flow is directed to the brain and heart. Catecholamines also control the levels of the vasoconstrictors renin, angiotensin II, and vasopressin. These general principles also apply to the neonate.

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Section: Blood Volume and Blood Pressurementioning

confidence: 99%

Control of Blood Pressure and the Distribution of Blood Flow

Versmold

1991

Int J Technol Assess Health Care

View full text Add to dashboard Cite

show abstract

Peripheral circulation in the newborn: Interaction of peripheral blood flow, blood pressure, blood volume, and blood viscosity

Cited by 1 publication

References 0 publications

Control of Blood Pressure and the Distribution of Blood Flow

Control of Blood Pressure and the Distribution of Blood Flow

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