Peripheral Markers in Alzheimer’s Disease

Letters to the Editor: Increase in Mean Cell Volume?a Possible Peripheral Marker for Alzheimer?s Disease?

“…No de®nitive peripheral marker for Alzheimer's disease has yet been found (Sweet and Zubenko, 1994). Changes in free radical activity (Volicer and Crino, 1990), abnormal aluminium pharmacokinetics (Hodgkins et al, 1993), apolipoprotein E genotype (Saunders et al, 1993) and raised mean cell volume (Prasher, 1994) have been recently proposed.…”