Peripheral modification of thermoregulatory function during heat acclimation.

Heat Acclimatization in Hot Summer for Ten Weeks Suppress the Sensitivity of Sweating in Response to Iontophoretically-administered Acetylcholine

“…The related finding of a depressed sensitivity of the sweat glands, following repeated ACh administration, supports this claim. Chen and Elizondo (1974) observed the depression of thermal sweating after repeated ACh iontophoresis, in support of our earlier data that showed that the suppression of the sweat gland response in a significant contributor to the suppression of sudomotor function in tropical natives Lee et al, , 2002Bae et al, 2006). In contrast to these observations, short-term heat acclimation increases the activity of the sweat glands.…”

“…In this study, we observed 0. (Chen and Elizondo, 1974). Considering the fact that the skin temperature difference in our study was only 0.31ºC, and the difference in the sweat volume was DIR 18%−AXR (1) 49%−AXR (2) 48% higher, we concluded that the higher skin temperature before acclimatization in July compared to after acclimatization in September was insufficient to account for the large difference in sweat output.…”

“…The density and capacity of the sweat glands may differ from one body region to another (Sato and Sato, 1983;Shibasaki et al, 1997;Kondo et al, 1998). However, the forearm sweat glands have widely been used to approximate sweating activity of whole body (Wyndham et al, 1964;Wyndham, 1967;Chen & Elizondo, 1974;Ogawa et al, 1982;Kondo et al, 2001). …”

Effects of sweat gland training by repeated local heating.

“…It has been generally recognized that the increased sweat response to heat load in association with heat acclimatization is due to both adaptive changes in the central thermoregulatory activity and increased secretory capacity of sweat glands, the latter of which has been considered to play a predominant role (Fox et al, 1964;CHEN and ELIZONDO, 1974). In our previous study (OGAWA and ASAYAMA, 1978), it was demonstrated that the potentiation of the secretory capacity of sweat glands precedes the more gradual changes in the activity of the central sudomotor mechanism in the course of experimental heat acclimation.…”

Mechanisms of heat acclimation and tolerance induced by exercise training and heat exposure

“…In contrast, several studies have supported the role of local changes in sweat gland function because of heat acclimation. For example, if regional temperature was maintained at a low temperature throughout a heat acclimation protocol, sweat responses of that region were not modified by heat acclimation 10) . Lorenzo and Minson 4) investigated whether changes in maximal vasodilator capacity of the skin and in vascular responsiveness to a given level of stimulation are altered by heat acclimation in trained individuals.…”