Peripheral neuropathy is a common manifestation of mitochondrial diseases: a single‐centre experience

Abstract

In conclusion, peripheral involvement in MD is frequent even if often mild or asymptomatic. The correct identification and characterization of peripheral neuropathy through electrophysiological studies represents another tile in the challenge of MD diagnosis.

Comorbidity of mitochondrial disease and dementia in patients with idiopathic polyneuropathy

“…Our finding of a strong association between MD and CIAP was expected as previous studies have shown a polyneuropathy prevalence of 12–45% among patients with mitochondrial disorders . Polyneuropathy is also a recognized clinically significant feature in several well‐defined mitochondrial syndromes .…”

Mitochondrial neuropathy: considerations on pathogenesis

“…As in our previous article [2], diabetes was reported in 15 cases, seven with neuropathy and eight without. All patients with diabetes were in treatment and the mean HbA1c value was 57.67 mmol/mol (range 46.0-85.0; normal value < 42.0), again excluding any correlation of diabetes or treatment with the presence of neuropathy.…”

“…These data confirm the importance of always screening patients with MD for neuropathy. Neuropathy was defined as indicated in Luigetti et al [2] and we used normative data from our laboratory obtained with the same electromyography (EMG) apparatus (Dantec Keypoint).…”

Advances and insights into neurological practice 2016−17

“…Neuromuscular disorders , trauma , neuro‐inflammation , headache and more general neurological topics complete the 2016 spectrum of the Journal's purview.…”