Peripheral T-cell Lymphoma of the Uvula: A Rare Entity

Abstract

Introduction: Extra-nodal exposition of T-cell non-hodgkin lymphoma (NHL) is extremely rare, and is frequently observed in patients with immune system dysfunction. Peripheral T-cell lymphoma does not express CD 56is rare. Malignant lymphoma of the uvula is exceedingly unusual. The current study reported a case of peripheral T-cell lymphoma of the uvula in an immunecompetent patient. Case presentation: The current study reported a case of peripheral T-cell lymphoma of the uvula in a 54-year-old male patient. The diagnosis was based on excisional biopsy and ancillary techniques. The patient was referred to the hemato-oncology ward for treatment. Conclusion: Considering the fact that the presentation of peripheral T-cell NHL in uvula is uncommon, a high index of suspicion is necessary to diagnose this grave disease. To the best of authors` knowledge, this case is the third case of T-cell lymphoma of the uvula in the English literature.

Lymphoma of the Uvula: Clinical, Morphological, Histopathological, and Genetic Characterization. A Nationwide Danish Study From 1980 to 2019

“…Lymphoma involving the uvula is a rare malignant condition not well-described, and only a few cases have been reported in the literature. All previously published and the present cases of uvular lymphomas are presented in Table 1 and provides an overview of demographics, clinical presentation, subtype, possible dissemination, stage, imaging, treatment, and outcome (6)(7)(8)(9)(10)(11)(12)(13). Two of the present cases (case 3 and 4) were classified as local extensions from a tonsillar lymphoma (Table 1).…”