Peripherally Inserted Central Catheters: Use at a Tertiary Care Pediatric Center

Patterns, risk factors and treatment associated with PICC-DVT in hospitalized adults: A nested case–control study

“…Because PICCs facilitate the delivery of intravenous treatments and phlebotomy in hospitalized patients, their use has substantially grown in this subset [1,12]. Increasing use has led to the recognition that PICCs are often associated with thrombosis among inpatients, a complication that increases morbidity, mortality and cost.…”

“…Owing to ease of insertion, versatility, and multitude of clinical roles, use of peripherally inserted central catheters (PICCs) has grown dramatically in hospitalized settings [1][2][3]. Despite their many advantages, accumulating data suggest that PICCs are associated with venous thromboembolism (VTE) including upper extremity deep vein thrombosis (PICC-DVT) and pulmonary embolism (PE) [4][5][6].…”

Revisiting the tale of venous thromboembolism in hospitalized medical patients

“…Between 2009 and 2012, the Agency of Healthcare Quality and Research Healthcare Utilization Project database demonstrates an almost eight-fold increase in principal discharge diagnoses of upper-extremity DVT across US hospitals [13]. Second (and as noted in this study), the burden of this problem may be driven by peripherally inserted central catheters, as the use of these devices has grown rapidly in hospitalized medical patients compared to central venous catheters [14]. In a systematic review and meta-analysis of > 60 studies, we found that peripherally inserted central catheters were associated with a 2.5-fold greater risk of DVT than acute, non-tunneled central venous catheters [15].…”

The establishment and evaluation of rabbit model for peripherally inserted central catheter

“…This catheter is made of silicone or polyurethane, and it can be inserted in the peripheral venous system with the catheter tip located in the superior vena cava 1 . It's not only used for administration of intravenous fluid, total parenteral nutrition, anticancer agents, antibiotics, and blood products, but also for the through line blood sampling in clinical 2 .…”